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Novel [l,2,4]triazolo[3,4-a]isoquinoline chalcones as new chemotherapeutic agents: Block IAP tyrosine kinase domain and induce both intrinsic and extrinsic pathways of apoptosis.
Mohamed MF, Sroor FM, Ibrahim NS, Salem GS, El-Sayed HH, Mahmoud MM, Wagdy MM, Ahmed AM, Mahmoud AT, Ibrahim SS, Ismail MM, Eldin SM, Saleh FM, Hassaneen HM, Abdelhamid IA. Mohamed MF, et al. Among authors: hassaneen hm. Invest New Drugs. 2021 Feb;39(1):98-110. doi: 10.1007/s10637-020-00987-2. Epub 2020 Aug 28. Invest New Drugs. 2021. PMID: 32856275
[1,2,4] Triazolo [3,4-a]isoquinoline chalcone derivative exhibits anticancer activity via induction of oxidative stress, DNA damage, and apoptosis in Ehrlich solid carcinoma-bearing mice.
WalyEldeen AA, El-Shorbagy HM, Hassaneen HM, Abdelhamid IA, Sabet S, Ibrahim SA. WalyEldeen AA, et al. Among authors: hassaneen hm. Naunyn Schmiedebergs Arch Pharmacol. 2022 Oct;395(10):1225-1238. doi: 10.1007/s00210-022-02269-5. Epub 2022 Jul 26. Naunyn Schmiedebergs Arch Pharmacol. 2022. PMID: 35881165 Free PMC article.
Theoretical and molecular mechanistic investigations of novel (3-(furan-2-yl)pyrazol-4-yl) chalcones against lung carcinoma cell line (A549).
Mohamed MF, Ibrahim NS, Saddiq AA, Almaghrabi OA, Al-Hazemi ME, Hassaneen HM, Abdelhamid IA. Mohamed MF, et al. Among authors: hassaneen hm. Naunyn Schmiedebergs Arch Pharmacol. 2023 Apr;396(4):719-736. doi: 10.1007/s00210-022-02344-x. Epub 2022 Dec 5. Naunyn Schmiedebergs Arch Pharmacol. 2023. PMID: 36469109 Free PMC article.
28 results