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Computational design of a modular protein sense-response system.
Glasgow AA, Huang YM, Mandell DJ, Thompson M, Ritterson R, Loshbaugh AL, Pellegrino J, Krivacic C, Pache RA, Barlow KA, Ollikainen N, Jeon D, Kelly MJS, Fraser JS, Kortemme T. Glasgow AA, et al. Among authors: kelly mjs. Science. 2019 Nov 22;366(6468):1024-1028. doi: 10.1126/science.aax8780. Science. 2019. PMID: 31754004 Free PMC article.
Systems-level effects of allosteric perturbations to a model molecular switch.
Perica T, Mathy CJP, Xu J, Jang GΜ, Zhang Y, Kaake R, Ollikainen N, Braberg H, Swaney DL, Lambright DG, Kelly MJS, Krogan NJ, Kortemme T. Perica T, et al. Among authors: kelly mjs. Nature. 2021 Nov;599(7883):152-157. doi: 10.1038/s41586-021-03982-6. Epub 2021 Oct 13. Nature. 2021. PMID: 34646016 Free PMC article.
Allosteric N-WASP activation by an inter-SH3 domain linker in Nck.
Okrut J, Prakash S, Wu Q, Kelly MJ, Taunton J. Okrut J, et al. Proc Natl Acad Sci U S A. 2015 Nov 24;112(47):E6436-45. doi: 10.1073/pnas.1510876112. Epub 2015 Nov 9. Proc Natl Acad Sci U S A. 2015. PMID: 26554011 Free PMC article.
32 results