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A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation.
Patel A, Lee HO, Jawerth L, Maharana S, Jahnel M, Hein MY, Stoynov S, Mahamid J, Saha S, Franzmann TM, Pozniakovski A, Poser I, Maghelli N, Royer LA, Weigert M, Myers EW, Grill S, Drechsel D, Hyman AA, Alberti S. Patel A, et al. Among authors: hyman aa. Cell. 2015 Aug 27;162(5):1066-77. doi: 10.1016/j.cell.2015.07.047. Cell. 2015. PMID: 26317470 Free article.
ATP as a biological hydrotrope.
Patel A, Malinovska L, Saha S, Wang J, Alberti S, Krishnan Y, Hyman AA. Patel A, et al. Among authors: hyman aa. Science. 2017 May 19;356(6339):753-756. doi: 10.1126/science.aaf6846. Science. 2017. PMID: 28522535
Protein condensates as aging Maxwell fluids.
Jawerth L, Fischer-Friedrich E, Saha S, Wang J, Franzmann T, Zhang X, Sachweh J, Ruer M, Ijavi M, Saha S, Mahamid J, Hyman AA, Jülicher F. Jawerth L, et al. Among authors: hyman aa. Science. 2020 Dec 11;370(6522):1317-1323. doi: 10.1126/science.aaw4951. Science. 2020. PMID: 33303613
HspB8 prevents aberrant phase transitions of FUS by chaperoning its folded RNA-binding domain.
Boczek EE, Fürsch J, Niedermeier ML, Jawerth L, Jahnel M, Ruer-Gruß M, Kammer KM, Heid P, Mediani L, Wang J, Yan X, Pozniakovski A, Poser I, Mateju D, Hubatsch L, Carra S, Alberti S, Hyman AA, Stengel F. Boczek EE, et al. Among authors: hyman aa. Elife. 2021 Sep 6;10:e69377. doi: 10.7554/eLife.69377. Elife. 2021. PMID: 34487489 Free PMC article.
299 results