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Genomics and Virulence of Fonsecaea pugnacius, Agent of Disseminated Chromoblastomycosis.
Bombassaro A, Schneider GX, Costa FF, Leão ACR, Soley BS, Medeiros F, da Silva NM, Lima BJFS, Castro RJA, Bocca AL, Baura VA, Balsanelli E, Pankievicz VCS, Hrysay NMC, Scola RH, Moreno LF, Azevedo CMPS, Souza EM, Gomes RR, de Hoog S, Vicente VA. Bombassaro A, et al. Among authors: castro rja. Front Genet. 2020 Aug 4;11:822. doi: 10.3389/fgene.2020.00822. eCollection 2020. Front Genet. 2020. PMID: 32849816 Free PMC article.
Kicking sleepers out of bed: Macrophages promote reactivation of dormant Cryptococcus neoformans by extracellular vesicle release and non-lytic exocytosis.
de Castro RJA, Marina CL, Sturny-Leclère A, Hoffmann C, Bürgel PH, Wong SSW, Aimanianda V, Varet H, Agrawal R, Bocca AL, Alanio A. de Castro RJA, et al. PLoS Pathog. 2023 Nov 30;19(11):e1011841. doi: 10.1371/journal.ppat.1011841. eCollection 2023 Nov. PLoS Pathog. 2023. PMID: 38033163 Free PMC article.
Engineered Fluorescent Strains of Cryptococcus neoformans: a Versatile Toolbox for Studies of Host-Pathogen Interactions and Fungal Biology, Including the Viable but Nonculturable State.
de Castro RJA, Rêgo MTAM, Brandão FS, Pérez ALA, De Marco JL, Poças-Fonseca MJ, Nichols C, Alspaugh JA, Felipe MSS, Alanio A, Bocca AL, Fernandes L. de Castro RJA, et al. Microbiol Spectr. 2022 Oct 26;10(5):e0150422. doi: 10.1128/spectrum.01504-22. Epub 2022 Aug 25. Microbiol Spectr. 2022. PMID: 36005449 Free PMC article.
Early immune response against Fonsecaea pedrosoi requires Dectin-2-mediated Th17 activity, whereas Th1 response, aided by Treg cells, is crucial for fungal clearance in later stage of experimental chromoblastomycosis.
Siqueira IM, Wüthrich M, Li M, Wang H, Las-Casas LO, de Castro RJA, Klein B, Bocca AL. Siqueira IM, et al. Among authors: de castro rja. PLoS Negl Trop Dis. 2020 Jun 15;14(6):e0008386. doi: 10.1371/journal.pntd.0008386. eCollection 2020 Jun. PLoS Negl Trop Dis. 2020. PMID: 32542003 Free PMC article.
Peptides ToAP3 and ToAP4 decrease release of inflammatory cytokines through TLR-4 blocking.
Veloso Júnior PHH, Simon KS, de Castro RJA, Coelho LC, Erazo FAH, de Souza ACB, das Neves RC, Lozano VF, Schwartz EF, Tavares AH, Mortari MR, Junqueira-Kipnis AP, Silva-Pereira I, Bocca AL. Veloso Júnior PHH, et al. Among authors: de castro rja. Biomed Pharmacother. 2019 Oct;118:109152. doi: 10.1016/j.biopha.2019.109152. Epub 2019 Jul 31. Biomed Pharmacother. 2019. PMID: 31376652 Free article.
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