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mRNA vaccine against malaria tailored for liver-resident memory T cells.
Ganley M, Holz LE, Minnell JJ, de Menezes MN, Burn OK, Poa KCY, Draper SL, English K, Chan STS, Anderson RJ, Compton BJ, Marshall AJ, Cozijnsen A, Chua YC, Ge Z, Farrand KJ, Mamum JC, Xu C, Cockburn IA, Yui K, Bertolino P, Gras S, Le Nours J, Rossjohn J, Fernandez-Ruiz D, McFadden GI, Ackerley DF, Painter GF, Hermans IF, Heath WR. Ganley M, et al. Among authors: holz le. Nat Immunol. 2023 Sep;24(9):1487-1498. doi: 10.1038/s41590-023-01562-6. Epub 2023 Jul 20. Nat Immunol. 2023. PMID: 37474653
The liver contains distinct interconnected networks of CX3CR1+ macrophages, XCR1+ type 1 and CD301a+ type 2 conventional dendritic cells embedded within portal tracts.
English K, Tan SY, Kwan R, Holz LE, Sierro F, McGuffog C, Kaisho T, Heath WR, MacDonald KP, McCaughan GW, Bowen DG, Bertolino P. English K, et al. Among authors: holz le. Immunol Cell Biol. 2022 Jul;100(6):394-408. doi: 10.1111/imcb.12559. Epub 2022 Jun 19. Immunol Cell Biol. 2022. PMID: 35718354 Free PMC article.
6″-Modifed α-GalCer-peptide conjugate vaccine candidates protect against liver-stage malaria.
Meijlink MA, Chua YC, Chan STS, Anderson RJ, Rosenberg MW, Cozijnsen A, Mollard V, McFadden GI, Draper SL, Holz LE, Hermans IF, Heath WR, Painter GF, Compton BJ. Meijlink MA, et al. Among authors: holz le. RSC Chem Biol. 2022 Mar 2;3(5):551-560. doi: 10.1039/d1cb00251a. eCollection 2022 May 11. RSC Chem Biol. 2022. PMID: 35656478 Free PMC article.
53 results