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Influenza virus repurposes the antiviral protein IFIT2 to promote translation of viral mRNAs.
Nat Microbiol. 2020 Dec;5(12):1490-1503. doi: 10.1038/s41564-020-0778-x. Epub 2020 Aug 24.
Nat Microbiol. 2020.
PMID: 32839537
Free PMC article.
Differential Splicing of ANP32A in Birds Alters Its Ability to Stimulate RNA Synthesis by Restricted Influenza Polymerase.
Baker SF, Ledwith MP, Mehle A.
Baker SF, et al. Among authors: ledwith mp.
Cell Rep. 2018 Sep 4;24(10):2581-2588.e4. doi: 10.1016/j.celrep.2018.08.012.
Cell Rep. 2018.
PMID: 30184493
Free PMC article.
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Alternative splicing liberates a cryptic cytoplasmic isoform of mitochondrial MECR that antagonizes influenza virus.
Baker SF, Meistermann H, Tzouros M, Baker A, Golling S, Polster JS, Ledwith MP, Gitter A, Augustin A, Javanbakht H, Mehle A.
Baker SF, et al. Among authors: ledwith mp.
PLoS Biol. 2022 Dec 21;20(12):e3001934. doi: 10.1371/journal.pbio.3001934. eCollection 2022 Dec.
PLoS Biol. 2022.
PMID: 36542656
Free PMC article.
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Cryptic proteins translated from deletion-containing viral genomes dramatically expand the influenza virus proteome.
Ranum JN, Ledwith MP, Alnaji FG, Diefenbacher M, Orton R, Sloan E, Guereca M, Feltman EM, Smollett K, da Silva Filipe A, Conley M, Russell AB, Brooke CB, Hutchinson E, Mehle A.
Ranum JN, et al. Among authors: ledwith mp.
bioRxiv [Preprint]. 2024 Feb 7:2023.12.12.570638. doi: 10.1101/2023.12.12.570638.
bioRxiv. 2024.
PMID: 38168266
Free PMC article.
Updated.
Preprint.
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Cryptic proteins translated from deletion-containing viral genomes dramatically expand the influenza virus proteome.
Ranum JN, Ledwith MP, Alnaji FG, Diefenbacher M, Orton R, Sloan E, Güereca M, Feltman EM, Smollett K, da Silva Filipe A, Conley M, Russell AB, Brooke CB, Hutchinson E, Mehle A.
Ranum JN, et al. Among authors: ledwith mp.
Nucleic Acids Res. 2024 Apr 12;52(6):3199-3212. doi: 10.1093/nar/gkae133.
Nucleic Acids Res. 2024.
PMID: 38407436
Free PMC article.
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Interferon Regulatory Factor 1 and Type I Interferon Cooperate To Control Acute Gammaherpesvirus Infection.
Mboko WP, Rekow MM, Ledwith MP, Lange PT, Schmitz KE, Anderson S, Tarakanova VL.
Mboko WP, et al. Among authors: ledwith mp.
J Virol. 2016 Dec 16;91(1):e01444-16. doi: 10.1128/JVI.01444-16. Print 2017 Jan 1.
J Virol. 2016.
PMID: 27795415
Free PMC article.
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ATM supports gammaherpesvirus replication by attenuating type I interferon pathway.
Darrah EJ, Stoltz KP, Ledwith M, Tarakanova VL.
Darrah EJ, et al.
Virology. 2017 Oct;510:137-146. doi: 10.1016/j.virol.2017.07.014. Epub 2017 Jul 18.
Virology. 2017.
PMID: 28732227
Free PMC article.
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