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β-Catenin safeguards the ground state of mousepluripotency by strengthening the robustness of the transcriptional apparatus.
Zhang M, Lai Y, Krupalnik V, Guo P, Guo X, Zhou J, Xu Y, Yu Z, Liu L, Jiang A, Li W, Abdul MM, Ma G, Li N, Fu X, Lv Y, Jiang M, Tariq M, Kanwal S, Liu H, Xu X, Zhang H, Huang Y, Wang L, Chen S, Babarinde IA, Luo Z, Wang D, Zhou T, Ward C, He M, Ibañez DP, Li Y, Zhou J, Yuan J, Feng Y, Arumugam K, Di Vicino U, Bao X, Wu G, Schambach A, Wang H, Sun H, Gao F, Qin B, Hutchins AP, Doble BW, Hartmann C, Cosma MP, Qin Y, Xu GL, Chen R, Volpe G, Chen L, Hanna JH, Esteban MA. Zhang M, et al. Among authors: schambach a. Sci Adv. 2020 Jul 17;6(29):eaba1593. doi: 10.1126/sciadv.aba1593. eCollection 2020 Jul. Sci Adv. 2020. PMID: 32832621 Free PMC article.
Rescue of ATP7B function in hepatocyte-like cells from Wilson's disease induced pluripotent stem cells using gene therapy or the chaperone drug curcumin.
Zhang S, Chen S, Li W, Guo X, Zhao P, Xu J, Chen Y, Pan Q, Liu X, Zychlinski D, Lu H, Tortorella MD, Schambach A, Wang Y, Pei D, Esteban MA. Zhang S, et al. Among authors: schambach a. Hum Mol Genet. 2011 Aug 15;20(16):3176-87. doi: 10.1093/hmg/ddr223. Epub 2011 May 18. Hum Mol Genet. 2011. PMID: 21593220
Modeling abnormal early development with induced pluripotent stem cells from aneuploid syndromes.
Li W, Wang X, Fan W, Zhao P, Chan YC, Chen S, Zhang S, Guo X, Zhang Y, Li Y, Cai J, Qin D, Li X, Yang J, Peng T, Zychlinski D, Hoffmann D, Zhang R, Deng K, Ng KM, Menten B, Zhong M, Wu J, Li Z, Chen Y, Schambach A, Tse HF, Pei D, Esteban MA. Li W, et al. Among authors: schambach a. Hum Mol Genet. 2012 Jan 1;21(1):32-45. doi: 10.1093/hmg/ddr435. Epub 2011 Sep 23. Hum Mol Genet. 2012. PMID: 21949351
Transcriptional pause release is a rate-limiting step for somatic cell reprogramming.
Liu L, Xu Y, He M, Zhang M, Cui F, Lu L, Yao M, Tian W, Benda C, Zhuang Q, Huang Z, Li W, Li X, Zhao P, Fan W, Luo Z, Li Y, Wu Y, Hutchins AP, Wang D, Tse HF, Schambach A, Frampton J, Qin B, Bao X, Yao H, Zhang B, Sun H, Pei D, Wang H, Wang J, Esteban MA. Liu L, et al. Among authors: schambach a. Cell Stem Cell. 2014 Nov 6;15(5):574-88. doi: 10.1016/j.stem.2014.09.018. Epub 2014 Oct 9. Cell Stem Cell. 2014. PMID: 25312495 Free article.
Cell transcriptomic atlas of the non-human primate Macaca fascicularis.
Han L, Wei X, Liu C, Volpe G, Zhuang Z, Zou X, Wang Z, Pan T, Yuan Y, Zhang X, Fan P, Guo P, Lai Y, Lei Y, Liu X, Yu F, Shangguan S, Lai G, Deng Q, Liu Y, Wu L, Shi Q, Yu H, Huang Y, Cheng M, Xu J, Liu Y, Wang M, Wang C, Zhang Y, Xie D, Yang Y, Yu Y, Zheng H, Wei Y, Huang F, Lei J, Huang W, Zhu Z, Lu H, Wang B, Wei X, Chen F, Yang T, Du W, Chen J, Xu S, An J, Ward C, Wang Z, Pei Z, Wong CW, Liu X, Zhang H, Liu M, Qin B, Schambach A, Isern J, Feng L, Liu Y, Guo X, Liu Z, Sun Q, Maxwell PH, Barker N, Muñoz-Cánoves P, Gu Y, Mulder J, Uhlen M, Tan T, Liu S, Yang H, Wang J, Hou Y, Xu X, Esteban MA, Liu L. Han L, et al. Among authors: schambach a. Nature. 2022 Apr;604(7907):723-731. doi: 10.1038/s41586-022-04587-3. Epub 2022 Apr 13. Nature. 2022. PMID: 35418686
A spatiotemporal atlas of mouse liver homeostasis and regeneration.
Xu J, Guo P, Hao S, Shangguan S, Shi Q, Volpe G, Huang K, Zuo J, An J, Yuan Y, Cheng M, Deng Q, Zhang X, Lai G, Nan H, Wu B, Shentu X, Wu L, Wei X, Jiang Y, Huang X, Pan F, Song Y, Li R, Wang Z, Liu C, Liu S, Li Y, Yang T, Xu Z, Du W, Li L, Ahmed T, You K, Dai Z, Li L, Qin B, Li Y, Lai L, Qin D, Chen J, Fan R, Li Y, Hou J, Ott M, Sharma AD, Cantz T, Schambach A, Kristiansen K, Hutchins AP, Göttgens B, Maxwell PH, Hui L, Xu X, Liu L, Chen A, Lai Y, Esteban MA. Xu J, et al. Among authors: schambach a. Nat Genet. 2024 May;56(5):953-969. doi: 10.1038/s41588-024-01709-7. Epub 2024 Apr 16. Nat Genet. 2024. PMID: 38627598
Generation of healthy mice from gene-corrected disease-specific induced pluripotent stem cells.
Wu G, Liu N, Rittelmeyer I, Sharma AD, Sgodda M, Zaehres H, Bleidissel M, Greber B, Gentile L, Han DW, Rudolph C, Steinemann D, Schambach A, Ott M, Schöler HR, Cantz T. Wu G, et al. Among authors: schambach a. PLoS Biol. 2011 Jul;9(7):e1001099. doi: 10.1371/journal.pbio.1001099. Epub 2011 Jul 12. PLoS Biol. 2011. PMID: 21765802 Free PMC article.
Sustained knockdown of a disease-causing gene in patient-specific induced pluripotent stem cells using lentiviral vector-based gene therapy.
Eggenschwiler R, Loya K, Wu G, Sharma AD, Sgodda M, Zychlinski D, Herr C, Steinemann D, Teckman J, Bals R, Ott M, Schambach A, Schöler HR, Cantz T. Eggenschwiler R, et al. Among authors: schambach a. Stem Cells Transl Med. 2013 Sep;2(9):641-54. doi: 10.5966/sctm.2013-0017. Epub 2013 Aug 7. Stem Cells Transl Med. 2013. PMID: 23926210 Free PMC article.
RAG1/2 knockout pigs with severe combined immunodeficiency.
Huang J, Guo X, Fan N, Song J, Zhao B, Ouyang Z, Liu Z, Zhao Y, Yan Q, Yi X, Schambach A, Frampton J, Esteban MA, Yang D, Yang H, Lai L. Huang J, et al. Among authors: schambach a. J Immunol. 2014 Aug 1;193(3):1496-503. doi: 10.4049/jimmunol.1400915. Epub 2014 Jun 27. J Immunol. 2014. PMID: 24973446
358 results