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Novel Blocker of Onco SK3 Channels Derived from Scorpion Toxin Tamapin and Active against Migration of Cancer Cells.
Mayorga-Flores M, Chantôme A, Melchor-Meneses CM, Domingo I, Titaux-Delgado GA, Galindo-Murillo R, Vandier C, Del Río-Portilla F. Mayorga-Flores M, et al. Among authors: vandier c. ACS Med Chem Lett. 2020 Jul 10;11(8):1627-1633. doi: 10.1021/acsmedchemlett.0c00300. eCollection 2020 Aug 13. ACS Med Chem Lett. 2020. PMID: 32832033 Free PMC article.
LKB1-SIK2 loss drives uveal melanoma proliferation and hypersensitivity to SLC8A1 and ROS inhibition.
Proteau S, Krossa I, Husser C, Guéguinou M, Sella F, Bille K, Irondelle M, Dalmasso M, Barouillet T, Cheli Y, Pisibon C, Arrighi N, Nahon-Estève S, Martel A, Gastaud L, Lassalle S, Mignen O, Brest P, Mazure NM, Bost F, Baillif S, Landreville S, Turcotte S, Hasson D, Carcamo S, Vandier C, Bernstein E, Yvan-Charvet L, Levesque MP, Ballotti R, Bertolotto C, Strub T. Proteau S, et al. Among authors: vandier c. EMBO Mol Med. 2023 Dec 7;15(12):e17719. doi: 10.15252/emmm.202317719. Epub 2023 Nov 15. EMBO Mol Med. 2023. PMID: 37966164 Free PMC article.
The SK3/K(Ca)2.3 potassium channel is a new cellular target for edelfosine.
Potier M, Chantome A, Joulin V, Girault A, Roger S, Besson P, Jourdan ML, LeGuennec JY, Bougnoux P, Vandier C. Potier M, et al. Among authors: vandier c. Br J Pharmacol. 2011 Jan;162(2):464-79. doi: 10.1111/j.1476-5381.2010.01044.x. Br J Pharmacol. 2011. PMID: 20955368 Free PMC article.
New alkyl-lipid blockers of SK3 channels reduce cancer cell migration and occurrence of metastasis.
Girault A, Haelters JP, Potier-Cartereau M, Chantome A, Pinault M, Marionneau-Lambot S, Oullier T, Simon G, Couthon-Gourvès H, Jaffrès PA, Corbel B, Bougnoux P, Joulin V, Vandier C. Girault A, et al. Among authors: vandier c. Curr Cancer Drug Targets. 2011 Nov;11(9):1111-25. doi: 10.2174/156800911798073069. Curr Cancer Drug Targets. 2011. PMID: 21999627
Targeting SKCa channels in cancer: potential new therapeutic approaches.
Girault A, Haelters JP, Potier-Cartereau M, Chantôme A, Jaffrés PA, Bougnoux P, Joulin V, Vandier C. Girault A, et al. Among authors: vandier c. Curr Med Chem. 2012;19(5):697-713. doi: 10.2174/092986712798992039. Curr Med Chem. 2012. PMID: 22204342 Review.
Pivotal role of the lipid Raft SK3-Orai1 complex in human cancer cell migration and bone metastases.
Chantôme A, Potier-Cartereau M, Clarysse L, Fromont G, Marionneau-Lambot S, Guéguinou M, Pagès JC, Collin C, Oullier T, Girault A, Arbion F, Haelters JP, Jaffrès PA, Pinault M, Besson P, Joulin V, Bougnoux P, Vandier C. Chantôme A, et al. Among authors: vandier c. Cancer Res. 2013 Aug 1;73(15):4852-61. doi: 10.1158/0008-5472.CAN-12-4572. Epub 2013 Jun 17. Cancer Res. 2013. PMID: 23774210
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