Neculai D - Search Results

1

Sunitinib inhibits RNase L by destabilizing its active dimer conformation.

Tang J, Wang Y, Zhou H, Ye Y, Talukdar M, Fu Z, Liu Z, Li J, Neculai D, Gao J, Huang H. Tang J, et al. Among authors: neculai d. Biochem J. 2020 Sep 18;477(17):3387-3399. doi: 10.1042/BCJ20200260. Biochem J. 2020. PMID: 32830849

2

In silico predicted structural and functional insights of all missense mutations on 2B domain of K1/K10 causing genodermatoses.

Banerjee S, Wu Q, Ying Y, Li Y, Shirota M, Neculai D, Li C. Banerjee S, et al. Among authors: neculai d. Oncotarget. 2016 Aug 16;7(33):52766-52780. doi: 10.18632/oncotarget.10599. Oncotarget. 2016. PMID: 27421141 Free PMC article.

3

Structure of the dual enzyme Ire1 reveals the basis for catalysis and regulation in nonconventional RNA splicing.

Lee KP, Dey M, Neculai D, Cao C, Dever TE, Sicheri F. Lee KP, et al. Among authors: neculai d. Cell. 2008 Jan 11;132(1):89-100. doi: 10.1016/j.cell.2007.10.057. Cell. 2008. PMID: 18191223 Free PMC article.

4

KVarPredDB: a database for predicting pathogenicity of missense sequence variants of keratin genes associated with genodermatoses.

Ying Y, Lu L, Banerjee S, Xu L, Zhao Q, Wu H, Li R, Xu X, Yu H, Neculai D, Xi Y, Yang F, Qin J, Li C. Ying Y, et al. Among authors: neculai d. Hum Genomics. 2020 Dec 7;14(1):45. doi: 10.1186/s40246-020-00295-z. Hum Genomics. 2020. PMID: 33287903 Free PMC article.

5

Atomic structure of the KEOPS complex: an ancient protein kinase-containing molecular machine.

Mao DY, Neculai D, Downey M, Orlicky S, Haffani YZ, Ceccarelli DF, Ho JS, Szilard RK, Zhang W, Ho CS, Wan L, Fares C, Rumpel S, Kurinov I, Arrowsmith CH, Durocher D, Sicheri F. Mao DY, et al. Among authors: neculai d. Mol Cell. 2008 Oct 24;32(2):259-75. doi: 10.1016/j.molcel.2008.10.002. Mol Cell. 2008. PMID: 18951093 Free PMC article.

6

PHC1 maintains pluripotency by organizing genome-wide chromatin interactions of the Nanog locus.

Chen L, Tong Q, Chen X, Jiang P, Yu H, Zhao Q, Sun L, Liu C, Gu B, Zheng Y, Fei L, Jiang X, Li W, Volpe G, Abdul MM, Guo G, Zhang J, Qian P, Sun Q, Neculai D, Esteban MA, Li C, Wen F, Ji J. Chen L, et al. Among authors: neculai d. Nat Commun. 2021 May 14;12(1):2829. doi: 10.1038/s41467-021-22871-0. Nat Commun. 2021. PMID: 33990559 Free PMC article.

7

Suprafacial orientation of the SCFCdc4 dimer accommodates multiple geometries for substrate ubiquitination.

Tang X, Orlicky S, Lin Z, Willems A, Neculai D, Ceccarelli D, Mercurio F, Shilton BH, Sicheri F, Tyers M. Tang X, et al. Among authors: neculai d. Cell. 2007 Jun 15;129(6):1165-76. doi: 10.1016/j.cell.2007.04.042. Cell. 2007. PMID: 17574027 Free article.

8

Archaeal aIF2B interacts with eukaryotic translation initiation factors eIF2alpha and eIF2Balpha: Implications for aIF2B function and eIF2B regulation.

Dev K, Santangelo TJ, Rothenburg S, Neculai D, Dey M, Sicheri F, Dever TE, Reeve JN, Hinnebusch AG. Dev K, et al. Among authors: neculai d. J Mol Biol. 2009 Sep 25;392(3):701-22. doi: 10.1016/j.jmb.2009.07.030. Epub 2009 Jul 17. J Mol Biol. 2009. PMID: 19616556 Free PMC article.

9

An allosteric inhibitor of the human Cdc34 ubiquitin-conjugating enzyme.

Ceccarelli DF, Tang X, Pelletier B, Orlicky S, Xie W, Plantevin V, Neculai D, Chou YC, Ogunjimi A, Al-Hakim A, Varelas X, Koszela J, Wasney GA, Vedadi M, Dhe-Paganon S, Cox S, Xu S, Lopez-Girona A, Mercurio F, Wrana J, Durocher D, Meloche S, Webb DR, Tyers M, Sicheri F. Ceccarelli DF, et al. Among authors: neculai d. Cell. 2011 Jun 24;145(7):1075-87. doi: 10.1016/j.cell.2011.05.039. Epub 2011 Jun 16. Cell. 2011. PMID: 21683433 Free article.

10

A strategy for modulation of enzymes in the ubiquitin system.

Ernst A, Avvakumov G, Tong J, Fan Y, Zhao Y, Alberts P, Persaud A, Walker JR, Neculai AM, Neculai D, Vorobyov A, Garg P, Beatty L, Chan PK, Juang YC, Landry MC, Yeh C, Zeqiraj E, Karamboulas K, Allali-Hassani A, Vedadi M, Tyers M, Moffat J, Sicheri F, Pelletier L, Durocher D, Raught B, Rotin D, Yang J, Moran MF, Dhe-Paganon S, Sidhu SS. Ernst A, et al. Among authors: neculai d, neculai am. Science. 2013 Feb 1;339(6119):590-5. doi: 10.1126/science.1230161. Epub 2013 Jan 3. Science. 2013. PMID: 23287719 Free PMC article.

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