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Fast skeletal myofibers of mdx mouse, model of Duchenne muscular dystrophy, express connexin hemichannels that lead to apoptosis.
Cea LA, Puebla C, Cisterna BA, Escamilla R, Vargas AA, Frank M, Martínez-Montero P, Prior C, Molano J, Esteban-Rodríguez I, Pascual I, Gallano P, Lorenzo G, Pian H, Barrio LC, Willecke K, Sáez JC. Cea LA, et al. Among authors: escamilla r. Cell Mol Life Sci. 2016 Jul;73(13):2583-99. doi: 10.1007/s00018-016-2132-2. Epub 2016 Jan 23. Cell Mol Life Sci. 2016. PMID: 26803842 Free PMC article.
De novo expression of functional connexins 43 and 45 hemichannels increases sarcolemmal permeability of skeletal myofibers during endotoxemia.
Cea LA, Balboa E, Vargas AA, Puebla C, Brañes MC, Escamilla R, Regueira T, Sáez JC. Cea LA, et al. Among authors: escamilla r. Biochim Biophys Acta Mol Basis Dis. 2019 Oct 1;1865(10):2765-2773. doi: 10.1016/j.bbadis.2019.06.014. Epub 2019 Jun 20. Biochim Biophys Acta Mol Basis Dis. 2019. PMID: 31228617 Free article.
A physiologic rise in cytoplasmic calcium ion signal increases pannexin1 channel activity via a C-terminus phosphorylation by CaMKII.
López X, Palacios-Prado N, Güiza J, Escamilla R, Fernández P, Vega JL, Rojas M, Marquez-Miranda V, Chamorro E, Cárdenas AM, Maldifassi MC, Martínez AD, Duarte Y, González-Nilo FD, Sáez JC. López X, et al. Among authors: escamilla r. Proc Natl Acad Sci U S A. 2021 Aug 10;118(32):e2108967118. doi: 10.1073/pnas.2108967118. Proc Natl Acad Sci U S A. 2021. PMID: 34301850 Free PMC article.
222 results