MacDonald CC - Search Results

1

A missense mutation in the CSTF2 gene that impairs the function of the RNA recognition motif and causes defects in 3' end processing is associated with intellectual disability in humans.

Grozdanov PN, Masoumzadeh E, Kalscheuer VM, Bienvenu T, Billuart P, Delrue MA, Latham MP, MacDonald CC. Grozdanov PN, et al. Among authors: macdonald cc. Nucleic Acids Res. 2020 Sep 25;48(17):9804-9821. doi: 10.1093/nar/gkaa689. Nucleic Acids Res. 2020. PMID: 32816001 Free PMC article.

2

The mRNA encoding tauCstF-64 is expressed ubiquitously in mouse tissues.

Huber Z, Monarez RR, Dass B, MacDonald CC. Huber Z, et al. Among authors: macdonald cc. Ann N Y Acad Sci. 2005 Dec;1061:163-72. doi: 10.1196/annals.1336.017. Ann N Y Acad Sci. 2005. PMID: 16467265

3

Polyadenylation proteins CstF-64 and tauCstF-64 exhibit differential binding affinities for RNA polymers.

Monarez RR, MacDonald CC, Dass B. Monarez RR, et al. Among authors: macdonald cc. Biochem J. 2007 Feb 1;401(3):651-8. doi: 10.1042/BJ20061097. Biochem J. 2007. PMID: 17029590 Free PMC article.

4

Loss of polyadenylation protein tauCstF-64 causes spermatogenic defects and male infertility.

Dass B, Tardif S, Park JY, Tian B, Weitlauf HM, Hess RA, Carnes K, Griswold MD, Small CL, Macdonald CC. Dass B, et al. Among authors: macdonald cc. Proc Natl Acad Sci U S A. 2007 Dec 18;104(51):20374-9. doi: 10.1073/pnas.0707589104. Epub 2007 Dec 12. Proc Natl Acad Sci U S A. 2007. PMID: 18077340 Free PMC article.

5

The hinge domain of the cleavage stimulation factor protein CstF-64 is essential for CstF-77 interaction, nuclear localization, and polyadenylation.

Hockert JA, Yeh HJ, MacDonald CC. Hockert JA, et al. Among authors: macdonald cc. J Biol Chem. 2010 Jan 1;285(1):695-704. doi: 10.1074/jbc.M109.061705. Epub 2009 Nov 3. J Biol Chem. 2010. PMID: 19887456 Free PMC article.

6

Spermatogenetic but not immunological defects in mice lacking the τCstF-64 polyadenylation protein.

Hockert KJ, Martincic K, Mendis-Handagama SM, Borghesi LA, Milcarek C, Dass B, MacDonald CC. Hockert KJ, et al. Among authors: macdonald cc. J Reprod Immunol. 2011 Apr;89(1):26-37. doi: 10.1016/j.jri.2011.01.018. Epub 2011 Apr 13. J Reprod Immunol. 2011. PMID: 21489638 Free PMC article.

7

Polyadenylation site-specific differences in the activity of the neuronal βCstF-64 protein in PC-12 cells.

Shankarling GS, MacDonald CC. Shankarling GS, et al. Among authors: macdonald cc. Gene. 2013 Oct 25;529(2):220-7. doi: 10.1016/j.gene.2013.08.007. Epub 2013 Aug 12. Gene. 2013. PMID: 23948079 Free PMC article.

8

High-throughput sequencing of RNA isolated by cross-linking and immunoprecipitation (HITS-CLIP) to determine sites of binding of CstF-64 on nascent RNAs.

Grozdanov PN, Macdonald CC. Grozdanov PN, et al. Among authors: macdonald cc. Methods Mol Biol. 2014;1125:187-208. doi: 10.1007/978-1-62703-971-0_17. Methods Mol Biol. 2014. PMID: 24590791 Free PMC article.

9

CstF-64 supports pluripotency and regulates cell cycle progression in embryonic stem cells through histone 3' end processing.

Youngblood BA, Grozdanov PN, MacDonald CC. Youngblood BA, et al. Among authors: macdonald cc. Nucleic Acids Res. 2014 Jul;42(13):8330-42. doi: 10.1093/nar/gku551. Epub 2014 Jun 23. Nucleic Acids Res. 2014. PMID: 24957598 Free PMC article.

10

Generation of plasmid vectors expressing FLAG-tagged proteins under the regulation of human elongation factor-1α promoter using Gibson assembly.

Grozdanov PN, MacDonald CC. Grozdanov PN, et al. Among authors: macdonald cc. J Vis Exp. 2015 Feb 9;(96):52235. doi: 10.3791/52235. J Vis Exp. 2015. PMID: 25742071 Free PMC article.

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