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Immune-evasive human islet-like organoids ameliorate diabetes.
Yoshihara E, O'Connor C, Gasser E, Wei Z, Oh TG, Tseng TW, Wang D, Cayabyab F, Dai Y, Yu RT, Liddle C, Atkins AR, Downes M, Evans RM. Yoshihara E, et al. Nature. 2020 Oct;586(7830):606-611. doi: 10.1038/s41586-020-2631-z. Epub 2020 Aug 19. Nature. 2020. PMID: 32814902 Free PMC article.
DNA methylation atlas of the mouse brain at single-cell resolution.
Liu H, Zhou J, Tian W, Luo C, Bartlett A, Aldridge A, Lucero J, Osteen JK, Nery JR, Chen H, Rivkin A, Castanon RG, Clock B, Li YE, Hou X, Poirion OB, Preissl S, Pinto-Duarte A, O'Connor C, Boggeman L, Fitzpatrick C, Nunn M, Mukamel EA, Zhang Z, Callaway EM, Ren B, Dixon JR, Behrens MM, Ecker JR. Liu H, et al. Nature. 2021 Oct;598(7879):120-128. doi: 10.1038/s41586-020-03182-8. Epub 2021 Oct 6. Nature. 2021. PMID: 34616061 Free PMC article.
Epigenomic diversity of cortical projection neurons in the mouse brain.
Zhang Z, Zhou J, Tan P, Pang Y, Rivkin AC, Kirchgessner MA, Williams E, Lee CT, Liu H, Franklin AD, Miyazaki PA, Bartlett A, Aldridge AI, Vu M, Boggeman L, Fitzpatrick C, Nery JR, Castanon RG, Rashid M, Jacobs MW, Ito-Cole T, O'Connor C, Pinto-Duartec A, Dominguez B, Smith JB, Niu SY, Lee KF, Jin X, Mukamel EA, Behrens MM, Ecker JR, Callaway EM. Zhang Z, et al. Nature. 2021 Oct;598(7879):167-173. doi: 10.1038/s41586-021-03223-w. Epub 2021 Oct 6. Nature. 2021. PMID: 34616065 Free PMC article.
The β1-adrenergic receptor links sympathetic nerves to T cell exhaustion.
Globig AM, Zhao S, Roginsky J, Maltez VI, Guiza J, Avina-Ochoa N, Heeg M, Araujo Hoffmann F, Chaudhary O, Wang J, Senturk G, Chen D, O'Connor C, Pfaff S, Germain RN, Schalper KA, Emu B, Kaech SM. Globig AM, et al. Nature. 2023 Oct;622(7982):383-392. doi: 10.1038/s41586-023-06568-6. Epub 2023 Sep 20. Nature. 2023. PMID: 37731001
Single-cell DNA methylome and 3D multi-omic atlas of the adult mouse brain.
Liu H, Zeng Q, Zhou J, Bartlett A, Wang BA, Berube P, Tian W, Kenworthy M, Altshul J, Nery JR, Chen H, Castanon RG, Zu S, Li YE, Lucero J, Osteen JK, Pinto-Duarte A, Lee J, Rink J, Cho S, Emerson N, Nunn M, O'Connor C, Wu Z, Stoica I, Yao Z, Smith KA, Tasic B, Luo C, Dixon JR, Zeng H, Ren B, Behrens MM, Ecker JR. Liu H, et al. Nature. 2023 Dec;624(7991):366-377. doi: 10.1038/s41586-023-06805-y. Epub 2023 Dec 13. Nature. 2023. PMID: 38092913 Free PMC article.
Brain-wide correspondence of neuronal epigenomics and distant projections.
Zhou J, Zhang Z, Wu M, Liu H, Pang Y, Bartlett A, Peng Z, Ding W, Rivkin A, Lagos WN, Williams E, Lee CT, Miyazaki PA, Aldridge A, Zeng Q, Salinda JLA, Claffey N, Liem M, Fitzpatrick C, Boggeman L, Yao Z, Smith KA, Tasic B, Altshul J, Kenworthy MA, Valadon C, Nery JR, Castanon RG, Patne NS, Vu M, Rashid M, Jacobs M, Ito T, Osteen J, Emerson N, Lee J, Cho S, Rink J, Huang HH, Pinto-Duartec A, Dominguez B, Smith JB, O'Connor C, Zeng H, Chen S, Lee KF, Mukamel EA, Jin X, Margarita Behrens M, Ecker JR, Callaway EM. Zhou J, et al. Nature. 2023 Dec;624(7991):355-365. doi: 10.1038/s41586-023-06823-w. Epub 2023 Dec 13. Nature. 2023. PMID: 38092919 Free PMC article.
miR-25/93 mediates hypoxia-induced immunosuppression by repressing cGAS.
Wu MZ, Cheng WC, Chen SF, Nieh S, O'Connor C, Liu CL, Tsai WW, Wu CJ, Martin L, Lin YS, Wu KJ, Lu LF, Izpisua Belmonte JC. Wu MZ, et al. Nat Cell Biol. 2017 Oct;19(10):1286-1296. doi: 10.1038/ncb3615. Epub 2017 Sep 18. Nat Cell Biol. 2017. PMID: 28920955 Free PMC article.
Robust single-cell DNA methylome profiling with snmC-seq2.
Luo C, Rivkin A, Zhou J, Sandoval JP, Kurihara L, Lucero J, Castanon R, Nery JR, Pinto-Duarte A, Bui B, Fitzpatrick C, O'Connor C, Ruga S, Van Eden ME, Davis DA, Mash DC, Behrens MM, Ecker JR. Luo C, et al. Nat Commun. 2018 Sep 20;9(1):3824. doi: 10.1038/s41467-018-06355-2. Nat Commun. 2018. PMID: 30237449 Free PMC article.
2,434 results