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PPT1 inhibition enhances the antitumor activity of anti-PD-1 antibody in melanoma.
Sharma G, Ojha R, Noguera-Ortega E, Rebecca VW, Attanasio J, Liu S, Piao S, Lee JJ, Nicastri MC, Harper SL, Ronghe A, Jain V, Winkler JD, Speicher DW, Mastio J, Gimotty PA, Xu X, Wherry EJ, Gabrilovich DI, Amaravadi RK. Sharma G, et al. Among authors: xu x. JCI Insight. 2020 Sep 3;5(17):e133225. doi: 10.1172/jci.insight.133225. JCI Insight. 2020. PMID: 32780726 Free PMC article.
Acquired resistance to BRAF inhibitors mediated by a RAF kinase switch in melanoma can be overcome by cotargeting MEK and IGF-1R/PI3K.
Villanueva J, Vultur A, Lee JT, Somasundaram R, Fukunaga-Kalabis M, Cipolla AK, Wubbenhorst B, Xu X, Gimotty PA, Kee D, Santiago-Walker AE, Letrero R, D'Andrea K, Pushparajan A, Hayden JE, Brown KD, Laquerre S, McArthur GA, Sosman JA, Nathanson KL, Herlyn M. Villanueva J, et al. Among authors: xu x. Cancer Cell. 2010 Dec 14;18(6):683-95. doi: 10.1016/j.ccr.2010.11.023. Cancer Cell. 2010. PMID: 21156289 Free PMC article.
IL-8 and cathepsin B as melanoma serum biomarkers.
Zhang H, Fu T, McGettigan S, Kumar S, Liu S, Speicher D, Schuchter L, Xu X. Zhang H, et al. Among authors: xu x. Int J Mol Sci. 2011;12(3):1505-18. doi: 10.3390/ijms12031505. Epub 2011 Feb 25. Int J Mol Sci. 2011. PMID: 21673904 Free PMC article.
Snail1 mediates hypoxia-induced melanoma progression.
Liu S, Kumar SM, Martin JS, Yang R, Xu X. Liu S, et al. Among authors: xu x. Am J Pathol. 2011 Dec;179(6):3020-31. doi: 10.1016/j.ajpath.2011.08.038. Epub 2011 Oct 11. Am J Pathol. 2011. PMID: 21996677 Free PMC article.
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