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Page 1
Targeted Cellular Micropharmacies: Cells Engineered for Localized Drug Delivery.
Gardner TJ, Bourne CM, Dacek MM, Kurtz K, Malviya M, Peraro L, Silberman PC, Vogt KC, Unti MJ, Brentjens R, Scheinberg D. Gardner TJ, et al. Among authors: brentjens r. Cancers (Basel). 2020 Aug 5;12(8):2175. doi: 10.3390/cancers12082175. Cancers (Basel). 2020. PMID: 32764348 Free PMC article. Review.
CAR T cell therapy: looking back and looking forward.
Davila ML, Brentjens RJ. Davila ML, et al. Among authors: brentjens rj. Nat Cancer. 2022 Dec;3(12):1418-1419. doi: 10.1038/s43018-022-00484-w. Nat Cancer. 2022. PMID: 36539498 No abstract available.
Pentostatin, cyclophosphamide, and rituximab is an active, well-tolerated regimen for patients with previously treated chronic lymphocytic leukemia.
Lamanna N, Kalaycio M, Maslak P, Jurcic JG, Heaney M, Brentjens R, Zelenetz AD, Horgan D, Gencarelli A, Panageas KS, Scheinberg DA, Weiss MA. Lamanna N, et al. Among authors: brentjens r. J Clin Oncol. 2006 Apr 1;24(10):1575-81. doi: 10.1200/JCO.2005.04.3836. Epub 2006 Mar 6. J Clin Oncol. 2006. PMID: 16520464
Tumor targeting with antibody-functionalized, radiolabeled carbon nanotubes.
McDevitt MR, Chattopadhyay D, Kappel BJ, Jaggi JS, Schiffman SR, Antczak C, Njardarson JT, Brentjens R, Scheinberg DA. McDevitt MR, et al. Among authors: brentjens r. J Nucl Med. 2007 Jul;48(7):1180-9. doi: 10.2967/jnumed.106.039131. J Nucl Med. 2007. PMID: 17607040 Free article.
Sequential therapy with fludarabine, high-dose cyclophosphamide, and rituximab in previously untreated patients with chronic lymphocytic leukemia produces high-quality responses: molecular remissions predict for durable complete responses.
Lamanna N, Jurcic JG, Noy A, Maslak P, Gencarelli AN, Panageas KS, Heaney ML, Brentjens RJ, Golde DW, Scheinberg DA, Zelenetz AD, Weiss MA. Lamanna N, et al. J Clin Oncol. 2009 Feb 1;27(4):491-7. doi: 10.1200/JCO.2008.16.4459. Epub 2008 Dec 15. J Clin Oncol. 2009. PMID: 19075280 Free PMC article.
Safety and persistence of adoptively transferred autologous CD19-targeted T cells in patients with relapsed or chemotherapy refractory B-cell leukemias.
Brentjens RJ, Rivière I, Park JH, Davila ML, Wang X, Stefanski J, Taylor C, Yeh R, Bartido S, Borquez-Ojeda O, Olszewska M, Bernal Y, Pegram H, Przybylowski M, Hollyman D, Usachenko Y, Pirraglia D, Hosey J, Santos E, Halton E, Maslak P, Scheinberg D, Jurcic J, Heaney M, Heller G, Frattini M, Sadelain M. Brentjens RJ, et al. Blood. 2011 Nov 3;118(18):4817-28. doi: 10.1182/blood-2011-04-348540. Epub 2011 Aug 17. Blood. 2011. PMID: 21849486 Free PMC article. Clinical Trial.
Phase 2 trial of a multivalent WT1 peptide vaccine (galinpepimut-S) in acute myeloid leukemia.
Maslak PG, Dao T, Bernal Y, Chanel SM, Zhang R, Frattini M, Rosenblat T, Jurcic JG, Brentjens RJ, Arcila ME, Rampal R, Park JH, Douer D, Katz L, Sarlis N, Tallman MS, Scheinberg DA. Maslak PG, et al. Among authors: brentjens rj. Blood Adv. 2018 Feb 13;2(3):224-234. doi: 10.1182/bloodadvances.2017014175. Blood Adv. 2018. PMID: 29386195 Free PMC article. Clinical Trial.
Engineering CAR-T cells to activate small-molecule drugs in situ.
Gardner TJ, Lee JP, Bourne CM, Wijewarnasuriya D, Kinarivala N, Kurtz KG, Corless BC, Dacek MM, Chang AY, Mo G, Nguyen KM, Brentjens RJ, Tan DS, Scheinberg DA. Gardner TJ, et al. Nat Chem Biol. 2022 Feb;18(2):216-225. doi: 10.1038/s41589-021-00932-1. Epub 2021 Dec 30. Nat Chem Biol. 2022. PMID: 34969970 Free PMC article.
Cellular therapies in acute lymphoblastic leukemia.
Park JH, Sauter C, Brentjens R. Park JH, et al. Among authors: brentjens r. Hematol Oncol Clin North Am. 2011 Dec;25(6):1281-301. doi: 10.1016/j.hoc.2011.09.015. Hematol Oncol Clin North Am. 2011. PMID: 22093587 Free PMC article. Review.
152 results