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Pharmacological profiling of JME-173, a novel mexiletine derivative combining dual anti-inflammatory/anti-spasmodic functions and limited action in Na+ channels.
Pinto DP, Coutinho DS, Carvalho KIM, Ferrero MR, Silva LVD, Silveira GPE, Silva DMD, Araújo JFG, Silva ACA, Pereira HM, Fonseca LBD, Faria RX, Souza MVN, Silva ETD, Santos-Filho OA, Costa JCSD, Amendoeira FC, Martins MA. Pinto DP, et al. Among authors: souza mvn. Eur J Pharmacol. 2020 Oct 15;885:173367. doi: 10.1016/j.ejphar.2020.173367. Epub 2020 Aug 1. Eur J Pharmacol. 2020. PMID: 32750364
Oral effectiveness of PMIC4, a novel hydroxyethylpiperazine analogue, in Leishmania amazonensis.
Vasconcelos MF, Cunha-Júnior EF, Andrade-Neto VV, Siqueira LM, d'Avila-Levy CM, Moreth M, Cunico W, Souza MV, Gomes CR, Torres-Santos EC. Vasconcelos MF, et al. Int J Parasitol Drugs Drug Resist. 2014 Nov 8;4(3):210-3. doi: 10.1016/j.ijpddr.2014.10.005. eCollection 2014 Dec. Int J Parasitol Drugs Drug Resist. 2014. PMID: 25516829 Free PMC article.
Investigation of the mechanism of action of mefloquine and derivatives against the parasite Echinococcus multilocularis.
Memedovski R, Preza M, Müller J, Kämpfer T, Rufener R, de Souza MVN, da Silva ET, de Andrade GF, Braga S, Uldry AC, Buchs N, Heller M, Lundström-Stadelmann B. Memedovski R, et al. Among authors: de souza mvn. Int J Parasitol Drugs Drug Resist. 2023 Apr;21:114-124. doi: 10.1016/j.ijpddr.2023.03.002. Epub 2023 Mar 9. Int J Parasitol Drugs Drug Resist. 2023. PMID: 36921443 Free PMC article.
Current leishmaniasis drug discovery.
Pinheiro AC, de Souza MVN. Pinheiro AC, et al. Among authors: de souza mvn. RSC Med Chem. 2022 Aug 26;13(9):1029-1043. doi: 10.1039/d1md00362c. eCollection 2022 Sep 21. RSC Med Chem. 2022. PMID: 36324493 Free PMC article. Review.
Mefloquine synergism with anti-tuberculosis drugs and correlation to membrane effects: Biologic, spectroscopic and molecular dynamics simulations studies.
Dos Santos MC, Scaini JLR, Lopes MVC, Rodrigues BG, Silva NO, Borges CRL, Dos Santos SC, Dos Santos Machado K, Werhli AV, da Silva PEA, Lourenço MCS, da Silva ET, de Souza MVN, de Lima VR, Gonçalves RSB. Dos Santos MC, et al. Among authors: de souza mvn. Bioorg Chem. 2021 May;110:104786. doi: 10.1016/j.bioorg.2021.104786. Epub 2021 Mar 2. Bioorg Chem. 2021. PMID: 33740676
165 results