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Pharmacological profiling of JME-173, a novel mexiletine derivative combining dual anti-inflammatory/anti-spasmodic functions and limited action in Na+ channels.
Pinto DP, Coutinho DS, Carvalho KIM, Ferrero MR, Silva LVD, Silveira GPE, Silva DMD, Araújo JFG, Silva ACA, Pereira HM, Fonseca LBD, Faria RX, Souza MVN, Silva ETD, Santos-Filho OA, Costa JCSD, Amendoeira FC, Martins MA. Pinto DP, et al. Among authors: faria rx. Eur J Pharmacol. 2020 Oct 15;885:173367. doi: 10.1016/j.ejphar.2020.173367. Epub 2020 Aug 1. Eur J Pharmacol. 2020. PMID: 32750364
JMF2-1, a lidocaine derivative acting on airways spasm and lung allergic inflammation in rats.
da Costa JC, Olsen PC, de Azeredo Siqueira R, de Frias Carvalho V, Serra MF, Alves LA, Faria RX, Xisto DG, Rocco PR, Cordeiro RS, Rodrigues E Silva PM, Martins MA. da Costa JC, et al. Among authors: faria rx. J Allergy Clin Immunol. 2007 Jan;119(1):219-25. doi: 10.1016/j.jaci.2006.08.037. Epub 2006 Oct 13. J Allergy Clin Immunol. 2007. PMID: 17208605
1-Aryl-1H- and 2-aryl-2H-1,2,3-triazole derivatives blockade P2X7 receptor in vitro and inflammatory response in vivo.
Gonzaga DTG, Ferreira LBG, Moreira Maramaldo Costa TE, von Ranke NL, Anastácio Furtado Pacheco P, Sposito Simões AP, Arruda JC, Dantas LP, de Freitas HR, de Melo Reis RA, Penido C, Bello ML, Castro HC, Rodrigues CR, Ferreira VF, Faria RX, da Silva FC. Gonzaga DTG, et al. Among authors: faria rx. Eur J Med Chem. 2017 Oct 20;139:698-717. doi: 10.1016/j.ejmech.2017.08.034. Epub 2017 Aug 16. Eur J Med Chem. 2017. PMID: 28858765
1,4-Naphthoquinones potently inhibiting P2X7 receptor activity.
Faria RX, Oliveira FH, Salles JP, Oliveira AS, von Ranke NL, Bello ML, Rodrigues CR, Castro HC, Louvis AR, Martins DL, Ferreira VF. Faria RX, et al. Eur J Med Chem. 2018 Jan 1;143:1361-1372. doi: 10.1016/j.ejmech.2017.10.033. Epub 2017 Oct 23. Eur J Med Chem. 2018. PMID: 29133043
69 results