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Development and validation of LC-MS/MS methods for the simultaneous quantification of sofosbuvir and its major metabolite (GS-331007) in blood plasma and cerebrospinal and seminal fluid: Application to a pilot clinical trial with a focus on Zika.
Biomed Chromatogr. 2023 May;37(5):e5606. doi: 10.1002/bmc.5606. Epub 2023 Mar 5.
Biomed Chromatogr. 2023.
PMID: 36797051
Clinical Trial.
Pharmacological profiling of JME-173, a novel mexiletine derivative combining dual anti-inflammatory/anti-spasmodic functions and limited action in Na+ channels.
Pinto DP, Coutinho DS, Carvalho KIM, Ferrero MR, Silva LVD, Silveira GPE, Silva DMD, Araújo JFG, Silva ACA, Pereira HM, Fonseca LBD, Faria RX, Souza MVN, Silva ETD, Santos-Filho OA, Costa JCSD, Amendoeira FC, Martins MA.
Pinto DP, et al. Among authors: araujo jfg.
Eur J Pharmacol. 2020 Oct 15;885:173367. doi: 10.1016/j.ejphar.2020.173367. Epub 2020 Aug 1.
Eur J Pharmacol. 2020.
PMID: 32750364
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