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Inhibition of hematopoietic protein tyrosine phosphatase augments and prolongs ERK1/2 and p38 activation.
Sergienko E, Xu J, Liu WH, Dahl R, Critton DA, Su Y, Brown BT, Chan X, Yang L, Bobkova EV, Vasile S, Yuan H, Rascon J, Colayco S, Sidique S, Cosford ND, Chung TD, Mustelin T, Page R, Lombroso PJ, Tautz L. Sergienko E, et al. Among authors: tautz l. ACS Chem Biol. 2012 Feb 17;7(2):367-77. doi: 10.1021/cb2004274. Epub 2011 Nov 17. ACS Chem Biol. 2012. PMID: 22070201 Free PMC article.
Design, Synthesis, and Characterization of an Orally Active Dual-Specific ULK1/2 Autophagy Inhibitor that Synergizes with the PARP Inhibitor Olaparib for the Treatment of Triple-Negative Breast Cancer.
Ren H, Bakas NA, Vamos M, Chaikuad A, Limpert AS, Wimer CD, Brun SN, Lambert LJ, Tautz L, Celeridad M, Sheffler DJ, Knapp S, Shaw RJ, Cosford NDP. Ren H, et al. Among authors: tautz l. J Med Chem. 2020 Dec 10;63(23):14609-14625. doi: 10.1021/acs.jmedchem.0c00873. Epub 2020 Nov 17. J Med Chem. 2020. PMID: 33200929 Free PMC article.
Discovery of novel furanylbenzamide inhibitors that target oncogenic tyrosine phosphatase SHP2 in leukemia cells.
Raveendra-Panickar D, Finlay D, Layng FI, Lambert LJ, Celeridad M, Zhao M, Barbosa K, De Backer LJS, Kwong E, Gosalia P, Rodiles S, Holleran J, Ardecky R, Grotegut S, Olson S, Hutchinson JH, Pasquale EB, Vuori K, Deshpande AJ, Cosford NDP, Tautz L. Raveendra-Panickar D, et al. Among authors: tautz l. J Biol Chem. 2022 Jan;298(1):101477. doi: 10.1016/j.jbc.2021.101477. Epub 2021 Dec 10. J Biol Chem. 2022. PMID: 34896393 Free PMC article.
Protein Tyrosine Phosphatase Biochemical Inhibition Assays.
Baranowski MR, Wu J, Han YN, Lambert LJ, Cosford NDP, Tautz L. Baranowski MR, et al. Among authors: tautz l. Bio Protoc. 2022 Sep 20;12(18):e4510. doi: 10.21769/BioProtoc.4510. eCollection 2022 Sep 20. Bio Protoc. 2022. PMID: 36248604 Free PMC article.
Yersinia phosphatase induces mitochondrially dependent apoptosis of T cells.
Bruckner S, Rhamouni S, Tautz L, Denault JB, Alonso A, Becattini B, Salvesen GS, Mustelin T. Bruckner S, et al. Among authors: tautz l. J Biol Chem. 2005 Mar 18;280(11):10388-94. doi: 10.1074/jbc.M408829200. Epub 2005 Jan 4. J Biol Chem. 2005. PMID: 15632192 Free article.
80 results