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Circulating unmethylated CHTOP and INS DNA fragments provide evidence of possible islet cell death in youth with obesity and diabetes.
Syed F, Tersey SA, Turatsinze JV, Felton JL, Kang NJ, Nelson JB, Sims EK, Defrance M, Bizet M, Fuks F, Cnop M, Bugliani M, Marchetti P, Ziegler AG, Bonifacio E, Webb-Robertson BJ, Balamurugan AN, Evans-Molina C, Eizirik DL, Mather KJ, Arslanian S, Mirmira RG. Syed F, et al. Among authors: bugliani m. Clin Epigenetics. 2020 Jul 31;12(1):116. doi: 10.1186/s13148-020-00906-5. Clin Epigenetics. 2020. PMID: 32736653 Free PMC article.
DNA methylation profiling identifies epigenetic dysregulation in pancreatic islets from type 2 diabetic patients.
Volkmar M, Dedeurwaerder S, Cunha DA, Ndlovu MN, Defrance M, Deplus R, Calonne E, Volkmar U, Igoillo-Esteve M, Naamane N, Del Guerra S, Masini M, Bugliani M, Marchetti P, Cnop M, Eizirik DL, Fuks F. Volkmar M, et al. Among authors: bugliani m. EMBO J. 2012 Mar 21;31(6):1405-26. doi: 10.1038/emboj.2011.503. Epub 2012 Jan 31. EMBO J. 2012. PMID: 22293752 Free PMC article.
RNA sequencing identifies dysregulation of the human pancreatic islet transcriptome by the saturated fatty acid palmitate.
Cnop M, Abdulkarim B, Bottu G, Cunha DA, Igoillo-Esteve M, Masini M, Turatsinze JV, Griebel T, Villate O, Santin I, Bugliani M, Ladriere L, Marselli L, McCarthy MI, Marchetti P, Sammeth M, Eizirik DL. Cnop M, et al. Among authors: bugliani m. Diabetes. 2014 Jun;63(6):1978-93. doi: 10.2337/db13-1383. Epub 2013 Dec 30. Diabetes. 2014. PMID: 24379348
Mast cells infiltrate pancreatic islets in human type 1 diabetes.
Martino L, Masini M, Bugliani M, Marselli L, Suleiman M, Boggi U, Nogueira TC, Filipponi F, Occhipinti M, Campani D, Dotta F, Syed F, Eizirik DL, Marchetti P, De Tata V. Martino L, et al. Among authors: bugliani m. Diabetologia. 2015 Nov;58(11):2554-62. doi: 10.1007/s00125-015-3734-1. Epub 2015 Aug 15. Diabetologia. 2015. PMID: 26276263
Persistent or Transient Human β Cell Dysfunction Induced by Metabolic Stress: Specific Signatures and Shared Gene Expression with Type 2 Diabetes.
Marselli L, Piron A, Suleiman M, Colli ML, Yi X, Khamis A, Carrat GR, Rutter GA, Bugliani M, Giusti L, Ronci M, Ibberson M, Turatsinze JV, Boggi U, De Simone P, De Tata V, Lopes M, Nasteska D, De Luca C, Tesi M, Bosi E, Singh P, Campani D, Schulte AM, Solimena M, Hecht P, Rady B, Bakaj I, Pocai A, Norquay L, Thorens B, Canouil M, Froguel P, Eizirik DL, Cnop M, Marchetti P. Marselli L, et al. Among authors: bugliani m. Cell Rep. 2020 Dec 1;33(9):108466. doi: 10.1016/j.celrep.2020.108466. Cell Rep. 2020. PMID: 33264613 Free article.
Enhanced signaling downstream of ribonucleic Acid-activated protein kinase-like endoplasmic reticulum kinase potentiates lipotoxic endoplasmic reticulum stress in human islets.
Ladrière L, Igoillo-Esteve M, Cunha DA, Brion JP, Bugliani M, Marchetti P, Eizirik DL, Cnop M. Ladrière L, et al. Among authors: bugliani m. J Clin Endocrinol Metab. 2010 Mar;95(3):1442-9. doi: 10.1210/jc.2009-2322. Epub 2010 Jan 15. J Clin Endocrinol Metab. 2010. PMID: 20080856
110 results