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Page 1
Ablation of the Brca1-Palb2 Interaction Phenocopies Fanconi Anemia in Mice.
Park D, Bergin SM, Jones D, Ru P, Koivisto CS, Jeon YJ, Sizemore GM, Kladney RD, Hadjis A, Shakya R, Ludwig T. Park D, et al. Among authors: sizemore gm. Cancer Res. 2020 Oct 1;80(19):4172-4184. doi: 10.1158/0008-5472.CAN-20-0486. Epub 2020 Jul 30. Cancer Res. 2020. PMID: 32732220
Genetic ablation of Smoothened in pancreatic fibroblasts increases acinar-ductal metaplasia.
Liu X, Pitarresi JR, Cuitiño MC, Kladney RD, Woelke SA, Sizemore GM, Nayak SG, Egriboz O, Schweickert PG, Yu L, Trela S, Schilling DJ, Halloran SK, Li M, Dutta S, Fernandez SA, Rosol TJ, Lesinski GB, Shakya R, Ludwig T, Konieczny SF, Leone G, Wu J, Ostrowski MC. Liu X, et al. Among authors: sizemore gm. Genes Dev. 2016 Sep 1;30(17):1943-55. doi: 10.1101/gad.283499.116. Epub 2016 Sep 15. Genes Dev. 2016. PMID: 27633013 Free PMC article.
Stromal PTEN inhibits the expansion of mammary epithelial stem cells through Jagged-1.
Sizemore GM, Balakrishnan S, Hammer AM, Thies KA, Trimboli AJ, Wallace JA, Sizemore ST, Kladney RD, Woelke SA, Yu L, Fernandez SA, Chakravarti A, Leone G, Ostrowski MC. Sizemore GM, et al. Among authors: sizemore st. Oncogene. 2017 Apr 20;36(16):2297-2308. doi: 10.1038/onc.2016.383. Epub 2016 Oct 31. Oncogene. 2017. PMID: 27797378 Free PMC article.
Stromal PDGFR-α Activation Enhances Matrix Stiffness, Impedes Mammary Ductal Development, and Accelerates Tumor Growth.
Hammer AM, Sizemore GM, Shukla VC, Avendano A, Sizemore ST, Chang JJ, Kladney RD, Cuitiño MC, Thies KA, Verfurth Q, Chakravarti A, Yee LD, Leone G, Song JW, Ghadiali SN, Ostrowski MC. Hammer AM, et al. Among authors: sizemore gm, sizemore st. Neoplasia. 2017 Jun;19(6):496-508. doi: 10.1016/j.neo.2017.04.004. Epub 2017 May 11. Neoplasia. 2017. PMID: 28501760 Free PMC article.
Synthetic Lethality of PARP Inhibition and Ionizing Radiation is p53-dependent.
Sizemore ST, Mohammad R, Sizemore GM, Nowsheen S, Yu H, Ostrowski MC, Chakravarti A, Xia F. Sizemore ST, et al. Among authors: sizemore gm. Mol Cancer Res. 2018 Jul;16(7):1092-1102. doi: 10.1158/1541-7786.MCR-18-0106. Epub 2018 Mar 28. Mol Cancer Res. 2018. PMID: 29592899 Free PMC article.
Stromal PTEN determines mammary epithelial response to radiotherapy.
Sizemore GM, Balakrishnan S, Thies KA, Hammer AM, Sizemore ST, Trimboli AJ, Cuitiño MC, Steck SA, Tozbikian G, Kladney RD, Shinde N, Das M, Park D, Majumder S, Krishnan S, Yu L, Fernandez SA, Chakravarti A, Shields PG, White JR, Yee LD, Rosol TJ, Ludwig T, Park M, Leone G, Ostrowski MC. Sizemore GM, et al. Among authors: sizemore st. Nat Commun. 2018 Jul 17;9(1):2783. doi: 10.1038/s41467-018-05266-6. Nat Commun. 2018. PMID: 30018330 Free PMC article.
Disruption of stromal hedgehog signaling initiates RNF5-mediated proteasomal degradation of PTEN and accelerates pancreatic tumor growth.
Pitarresi JR, Liu X, Avendano A, Thies KA, Sizemore GM, Hammer AM, Hildreth BE 3rd, Wang DJ, Steck SA, Donohue S, Cuitiño MC, Kladney RD, Mace TA, Chang JJ, Ennis CS, Li H, Reeves RH, Blackshaw S, Zhang J, Yu L, Fernandez SA, Frankel WL, Bloomston M, Rosol TJ, Lesinski GB, Konieczny SF, Guttridge DC, Rustgi AK, Leone G, Song JW, Wu J, Ostrowski MC. Pitarresi JR, et al. Among authors: sizemore gm. Life Sci Alliance. 2018 Oct 26;1(5):e201800190. doi: 10.26508/lsa.201800190. eCollection 2018 Oct. Life Sci Alliance. 2018. PMID: 30456390 Free PMC article.
PTEN expression by an oncolytic herpesvirus directs T-cell mediated tumor clearance.
Russell L, Swanner J, Jaime-Ramirez AC, Wang Y, Sprague A, Banasavadi-Siddegowda Y, Yoo JY, Sizemore GM, Kladney R, Zhang J, Lehman NL, Ostrowski MC, Hong B, Caligiuri M, Yu J, Kaur B. Russell L, et al. Among authors: sizemore gm. Nat Commun. 2018 Nov 27;9(1):5006. doi: 10.1038/s41467-018-07344-1. Nat Commun. 2018. PMID: 30479334 Free PMC article.
Abrupt involution induces inflammation, estrogenic signaling, and hyperplasia linking lack of breastfeeding with increased risk of breast cancer.
Basree MM, Shinde N, Koivisto C, Cuitino M, Kladney R, Zhang J, Stephens J, Palettas M, Zhang A, Kim HK, Acero-Bedoya S, Trimboli A, Stover DG, Ludwig T, Ganju R, Weng D, Shields P, Freudenheim J, Leone GW, Sizemore GM, Majumder S, Ramaswamy B. Basree MM, et al. Among authors: sizemore gm. Breast Cancer Res. 2019 Jul 17;21(1):80. doi: 10.1186/s13058-019-1163-7. Breast Cancer Res. 2019. PMID: 31315645 Free PMC article.
Stromal Platelet-Derived Growth Factor Receptor-β Signaling Promotes Breast Cancer Metastasis in the Brain.
Thies KA, Hammer AM, Hildreth BE 3rd, Steck SA, Spehar JM, Kladney RD, Geisler JA, Das M, Russell LO, Bey JF 4th, Bolyard CM, Pilarski R, Trimboli AJ, Cuitiño MC, Koivisto CS, Stover DG, Schoenfield L, Otero J, Godbout JP, Chakravarti A, Ringel MD, Ramaswamy B, Li Z, Kaur B, Leone G, Ostrowski MC, Sizemore ST, Sizemore GM. Thies KA, et al. Among authors: sizemore gm, sizemore st. Cancer Res. 2021 Feb 1;81(3):606-618. doi: 10.1158/0008-5472.CAN-19-3731. Epub 2020 Apr 23. Cancer Res. 2021. PMID: 32327406 Free PMC article.
43 results