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Targeting GM-CSF in COVID-19 Pneumonia: Rationale and Strategies.
Bonaventura A, Vecchié A, Wang TS, Lee E, Cremer PC, Carey B, Rajendram P, Hudock KM, Korbee L, Van Tassell BW, Dagna L, Abbate A. Bonaventura A, et al. Among authors: cremer pc. Front Immunol. 2020 Jul 3;11:1625. doi: 10.3389/fimmu.2020.01625. eCollection 2020. Front Immunol. 2020. PMID: 32719685 Free PMC article. Review.
Canakinumab to reduce deterioration of cardiac and respiratory function in SARS-CoV-2 associated myocardial injury with heightened inflammation (canakinumab in Covid-19 cardiac injury: The three C study).
Sheng CC, Sahoo D, Dugar S, Prada RA, Wang TKM, Abou Hassan OK, Brennan D, Culver DA, Rajendram P, Duggal A, Lincoff AM, Nissen SE, Menon V, Cremer PC. Sheng CC, et al. Among authors: cremer pc. Clin Cardiol. 2020 Oct;43(10):1055-1063. doi: 10.1002/clc.23451. Epub 2020 Aug 24. Clin Cardiol. 2020. PMID: 32830894 Free PMC article.
RHAPSODY: Rationale for and design of a pivotal Phase 3 trial to assess efficacy and safety of rilonacept, an interleukin-1α and interleukin-1β trap, in patients with recurrent pericarditis.
Klein AL, Imazio M, Brucato A, Cremer P, LeWinter M, Abbate A, Lin D, Martini A, Beutler A, Chang S, Fang F, Gervais A, Perrin R, Paolini JF. Klein AL, et al. Am Heart J. 2020 Oct;228:81-90. doi: 10.1016/j.ahj.2020.07.004. Epub 2020 Jul 14. Am Heart J. 2020. PMID: 32866928 Clinical Trial.
Phase 3 Trial of Interleukin-1 Trap Rilonacept in Recurrent Pericarditis.
Klein AL, Imazio M, Cremer P, Brucato A, Abbate A, Fang F, Insalaco A, LeWinter M, Lewis BS, Lin D, Luis SA, Nicholls SJ, Pano A, Wheeler A, Paolini JF; RHAPSODY Investigators. Klein AL, et al. N Engl J Med. 2021 Jan 7;384(1):31-41. doi: 10.1056/NEJMoa2027892. Epub 2020 Nov 16. N Engl J Med. 2021. PMID: 33200890 Clinical Trial.
Mavrilimumab in patients with severe COVID-19 pneumonia and systemic hyperinflammation (MASH-COVID): an investigator initiated, multicentre, double-blind, randomised, placebo-controlled trial.
Cremer PC, Abbate A, Hudock K, McWilliams C, Mehta J, Chang SY, Sheng CC, Van Tassell B, Bonaventura A, Vecchié A, Carey B, Wang Q, Wolski KE, Rajendram P, Duggal A, Wang TS, Paolini JF, Trapnell BC; MASH-COVID study group. Cremer PC, et al. Lancet Rheumatol. 2021 Jun;3(6):e410-e418. doi: 10.1016/S2665-9913(21)00070-9. Epub 2021 Mar 17. Lancet Rheumatol. 2021. PMID: 33754144 Free PMC article.
Advances in pharmacotherapy for acute and recurrent pericarditis.
Vecchié A, Del Buono MG, Mauro AG, Cremer PC, Imazio M, Klein AL, Abbate A, Dentali F, Bonaventura A. Vecchié A, et al. Among authors: cremer pc. Expert Opin Pharmacother. 2022 Apr;23(6):681-691. doi: 10.1080/14656566.2022.2054327. Epub 2022 Mar 20. Expert Opin Pharmacother. 2022. PMID: 35311434 Review.
Double-blind randomized proof-of-concept trial of canakinumab in patients with COVID-19 associated cardiac injury and heightened inflammation.
Cremer PC, Sheng CC, Sahoo D, Dugar S, Prada RA, Wang TKM, Hassan OKA, Hernandez-Montfort J, Wolinsky DA, Culver DA, Rajendram P, Duggal A, Brennan DM, Wolski KE, Lincoff AM, Nissen SE, Menon V. Cremer PC, et al. Eur Heart J Open. 2021 Jul 29;1(1):oeab002. doi: 10.1093/ehjopen/oeab002. eCollection 2021 Aug. Eur Heart J Open. 2021. PMID: 35923169 Free PMC article.
Anakinra for corticosteroid-dependent and colchicine-resistant pericarditis: The IRAP (International Registry of Anakinra for Pericarditis) study.
Imazio M, Andreis A, De Ferrari GM, Cremer PC, Mardigyan V, Maestroni S, Luis SA, Lopalco G, Emmi G, Lotan D, Marcolongo R, Lazaros G, De Biasio M, Cantarini L, Dagna L, Cercek AC, Pivetta E, Varma B, Berkson L, Tombetti E, Iannone F, Prisco D, Caforio ALP, Vassilopoulos D, Tousoulis D, De Luca G, Giustetto C, Rinaldi M, Oh JK, Klein AL, Brucato A, Adler Y. Imazio M, et al. Among authors: cremer pc. Eur J Prev Cardiol. 2020 Jun;27(9):956-964. doi: 10.1177/2047487319879534. Epub 2019 Oct 15. Eur J Prev Cardiol. 2020. PMID: 31610707 Free article.
157 results