Elevated truncated oxidized phospholipids as a factor exacerbating ALI in the aging lungs.
Ke Y, Karki P, Kim J, Son S, Berdyshev E, Bochkov VN, Birukova AA, Birukov KG.
Ke Y, et al. Among authors: kim j.
FASEB J. 2019 Mar;33(3):3887-3900. doi: 10.1096/fj.201800981R. Epub 2018 Dec 6.
FASEB J. 2019.
PMID: 30521374
Free PMC article.
These results demonstrate an age-dependent increase in Tr-OxPL production under basal conditions and augmented Tr-OxPL generation upon inflammatory stimulation, suggesting a major role for elevated Tr-OxPLs in more severe ALI and delayed resolution in aging lungs.-Ke, Y., Karki, …
These results demonstrate an age-dependent increase in Tr-OxPL production under basal conditions and augmented Tr-OxPL generation upon infla …