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SIRT7 deficiency suppresses inflammation, induces EndoMT, and increases vascular permeability in primary pulmonary endothelial cells.
Wyman AE, Nguyen TTT, Karki P, Tulapurkar ME, Zhang CO, Kim J, Feng TG, Dabo AJ, Todd NW, Luzina IG, Geraghty P, Foronjy RF, Hasday JD, Birukova AA, Atamas SP, Birukov KG. Wyman AE, et al. Among authors: karki p. Sci Rep. 2020 Jul 27;10(1):12497. doi: 10.1038/s41598-020-69236-z. Sci Rep. 2020. PMID: 32719338 Free PMC article.
Lipid mediators in the regulation of endothelial barriers.
Karki P, Birukov KG. Karki P, et al. Tissue Barriers. 2018 Jan 2;6(1):e1385573. doi: 10.1080/21688370.2017.1385573. Epub 2017 Oct 30. Tissue Barriers. 2018. PMID: 29083949 Free PMC article. Review.
Elevated truncated oxidized phospholipids as a factor exacerbating ALI in the aging lungs.
Ke Y, Karki P, Kim J, Son S, Berdyshev E, Bochkov VN, Birukova AA, Birukov KG. Ke Y, et al. Among authors: karki p. FASEB J. 2019 Mar;33(3):3887-3900. doi: 10.1096/fj.201800981R. Epub 2018 Dec 6. FASEB J. 2019. PMID: 30521374 Free PMC article.
These results demonstrate an age-dependent increase in Tr-OxPL production under basal conditions and augmented Tr-OxPL generation upon inflammatory stimulation, suggesting a major role for elevated Tr-OxPLs in more severe ALI and delayed resolution in aging lungs.-Ke, Y., Kark …
These results demonstrate an age-dependent increase in Tr-OxPL production under basal conditions and augmented Tr-OxPL generation upon infla …
274 results