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Gut microbiota drive the development of neuroinflammatory response in cirrhosis in mice.
Kang DJ, Betrapally NS, Ghosh SA, Sartor RB, Hylemon PB, Gillevet PM, Sanyal AJ, Heuman DM, Carl D, Zhou H, Liu R, Wang X, Yang J, Jiao C, Herzog J, Lippman HR, Sikaroodi M, Brown RR, Bajaj JS. Kang DJ, et al. Among authors: brown rr. Hepatology. 2016 Oct;64(4):1232-48. doi: 10.1002/hep.28696. Epub 2016 Jul 29. Hepatology. 2016. PMID: 27339732 Free PMC article.
Gut microbial RNA and DNA analysis predicts hospitalizations in cirrhosis.
Bajaj JS, Thacker LR, Fagan A, White MB, Gavis EA, Hylemon PB, Brown R, Acharya C, Heuman DM, Fuchs M, Dalmet S, Sikaroodi M, Gillevet PM. Bajaj JS, et al. Among authors: brown r. JCI Insight. 2018 Mar 8;3(5):e98019. doi: 10.1172/jci.insight.98019. JCI Insight. 2018. PMID: 29515036 Free PMC article. Clinical Trial.
Diet affects gut microbiota and modulates hospitalization risk differentially in an international cirrhosis cohort.
Bajaj JS, Idilman R, Mabudian L, Hood M, Fagan A, Turan D, White MB, Karakaya F, Wang J, Atalay R, Hylemon PB, Gavis EA, Brown R, Thacker LR, Acharya C, Heuman DM, Sikaroodi M, Gillevet PM. Bajaj JS, et al. Among authors: brown r. Hepatology. 2018 Jul;68(1):234-247. doi: 10.1002/hep.29791. Epub 2018 May 10. Hepatology. 2018. PMID: 29350768
TMPRSS2-mediated SARS-CoV-2 uptake boosts innate immune activation, enhances cytopathology, and drives convergent virus evolution.
Qu B, Miskey C, Gömer A, Kleinert RDV, Ibanez SC, Eberle R, Ebenig A, Postmus D, Nocke MK, Herrmann M, Itotia TK, Herrmann ST, Heinen N, Höck S, Hastert FD, von Rhein C, Schürmann C, Li X, van Zandbergen G, Widera M, Ciesek S, Schnierle BS, Tarr AW, Steinmann E, Goffinet C, Pfaender S, Locker JK, Mühlebach MD, Todt D, Brown RJP. Qu B, et al. Among authors: brown rjp. Proc Natl Acad Sci U S A. 2024 Jun 4;121(23):e2407437121. doi: 10.1073/pnas.2407437121. Epub 2024 May 30. Proc Natl Acad Sci U S A. 2024. PMID: 38814864
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