Dellinger RW - Search Results

1

Safety Assessment of High-Purity, Synthetic Nicotinamide Riboside (NR-E) in a 90-Day Repeated Dose Oral Toxicity Study, With a 28-Day Recovery Arm.

Marinescu AG, Chen J, Holmes HE, Guarente L, Mendes O, Morris M, Dellinger RW. Marinescu AG, et al. Among authors: dellinger rw. Int J Toxicol. 2020 Jul/Aug;39(4):307-320. doi: 10.1177/1091581820927406. Int J Toxicol. 2020. PMID: 32715855

2

Nicotinamide riboside with pterostilbene (NRPT) increases NAD⁺ in patients with acute kidney injury (AKI): a randomized, double-blind, placebo-controlled, stepwise safety study of escalating doses of NRPT in patients with AKI.

Simic P, Vela Parada XF, Parikh SM, Dellinger R, Guarente LP, Rhee EP. Simic P, et al. BMC Nephrol. 2020 Aug 13;21(1):342. doi: 10.1186/s12882-020-02006-1. BMC Nephrol. 2020. PMID: 32791973 Free PMC article. Clinical Trial.

3

Repeat dose NRPT (nicotinamide riboside and pterostilbene) increases NAD⁺ levels in humans safely and sustainably: a randomized, double-blind, placebo-controlled study.

Dellinger RW, Santos SR, Morris M, Evans M, Alminana D, Guarente L, Marcotulli E. Dellinger RW, et al. NPJ Aging Mech Dis. 2017 Nov 24;3:17. doi: 10.1038/s41514-017-0016-9. eCollection 2017. NPJ Aging Mech Dis. 2017. PMID: 29184669 Free PMC article.

4

Nicotinamide riboside and pterostilbene reduces markers of hepatic inflammation in NAFLD: A double-blind, placebo-controlled clinical trial.

Dellinger RW, Holmes HE, Hu-Seliger T, Butt RW, Harrison SA, Mozaffarian D, Chen O, Guarente L. Dellinger RW, et al. Hepatology. 2023 Sep 1;78(3):863-877. doi: 10.1002/hep.32778. Epub 2022 Nov 22. Hepatology. 2023. PMID: 36082508 Clinical Trial.

5

Erratum: Author Correction: Repeat dose NRPT (nicotinamide riboside and pterostilbene) increases NAD⁺ levels in humans safely and sustainably: a randomized, double-blind, placebo-controlled study.

Dellinger RW, Santos SR, Morris M, Evans M, Alminana D, Guarente L, Marcotulli E. Dellinger RW, et al. NPJ Aging Mech Dis. 2018 Aug 20;4:8. doi: 10.1038/s41514-018-0027-1. eCollection 2018. NPJ Aging Mech Dis. 2018. PMID: 30155270 Free PMC article.

6

Efficacy and tolerability of EH301 for amyotrophic lateral sclerosis: a randomized, double-blind, placebo-controlled human pilot study.

de la Rubia JE, Drehmer E, Platero JL, Benlloch M, Caplliure-Llopis J, Villaron-Casales C, de Bernardo N, AlarcÓn J, Fuente C, Carrera S, Sancho D, GarcÍa-Pardo P, Pascual R, JuÁrez M, Cuerda-Ballester M, Forner A, Sancho-Castillo S, Barrios C, Obrador E, Marchio P, Salvador R, Holmes HE, Dellinger RW, Guarente L, Estrela JM. de la Rubia JE, et al. Among authors: dellinger rw. Amyotroph Lateral Scler Frontotemporal Degener. 2019 Feb;20(1-2):115-122. doi: 10.1080/21678421.2018.1536152. Epub 2019 Jan 22. Amyotroph Lateral Scler Frontotemporal Degener. 2019. PMID: 30668199 Clinical Trial.

7

Gene expression profiles in sporadic ALS fibroblasts define disease subtypes and the metabolic effects of the investigational drug EH301.

Fels JA, Casalena G, Konrad C, Holmes HE, Dellinger RW, Manfredi G. Fels JA, et al. Among authors: dellinger rw. Hum Mol Genet. 2022 Oct 10;31(20):3458-3477. doi: 10.1093/hmg/ddac118. Hum Mol Genet. 2022. PMID: 35652455 Free PMC article.

8

A randomized placebo-controlled trial of nicotinamide riboside and pterostilbene supplementation in experimental muscle injury in elderly individuals.

Jensen JB, Dollerup OL, Møller AB, Billeskov TB, Dalbram E, Chubanava S, Damgaard MV, Dellinger RW, Trošt K, Moritz T, Ringgaard S, Møller N, Treebak JT, Farup J, Jessen N. Jensen JB, et al. Among authors: dellinger rw. JCI Insight. 2022 Oct 10;7(19):e158314. doi: 10.1172/jci.insight.158314. JCI Insight. 2022. PMID: 35998039 Free PMC article. Clinical Trial.

9

Intravenous nicotinamide riboside elevates mouse skeletal muscle NAD⁺ without impacting respiratory capacity or insulin sensitivity.

Damgaard MV, Nielsen TS, Basse AL, Chubanava S, Trost K, Moritz T, Dellinger RW, Larsen S, Treebak JT. Damgaard MV, et al. Among authors: dellinger rw. iScience. 2022 Feb 2;25(2):103863. doi: 10.1016/j.isci.2022.103863. eCollection 2022 Feb 18. iScience. 2022. PMID: 35198907 Free PMC article.

10

Nicotinamide riboside is uniquely and orally bioavailable in mice and humans.

Trammell SA, Schmidt MS, Weidemann BJ, Redpath P, Jaksch F, Dellinger RW, Li Z, Abel ED, Migaud ME, Brenner C. Trammell SA, et al. Among authors: dellinger rw. Nat Commun. 2016 Oct 10;7:12948. doi: 10.1038/ncomms12948. Nat Commun. 2016. PMID: 27721479 Free PMC article.

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