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Elucidating the mechanisms by which disulfiram protects against obesity and metabolic syndrome.
Bernier M, Harney D, Koay YC, Diaz A, Singh A, Wahl D, Pulpitel T, Ali A, Guiterrez V, Mitchell SJ, Kim EY, Mach J, Price NL, Aon MA, LeCouteur DG, Cogger VC, Fernandez-Hernando C, O'Sullivan J, Larance M, Cuervo AM, de Cabo R. Bernier M, et al. Among authors: de cabo r. NPJ Aging Mech Dis. 2020 Jul 21;6:8. doi: 10.1038/s41514-020-0046-6. eCollection 2020. NPJ Aging Mech Dis. 2020. PMID: 32714562 Free PMC article.
Nrf2 mediates cancer protection but not prolongevity induced by caloric restriction.
Pearson KJ, Lewis KN, Price NL, Chang JW, Perez E, Cascajo MV, Tamashiro KL, Poosala S, Csiszar A, Ungvari Z, Kensler TW, Yamamoto M, Egan JM, Longo DL, Ingram DK, Navas P, de Cabo R. Pearson KJ, et al. Among authors: de cabo r. Proc Natl Acad Sci U S A. 2008 Feb 19;105(7):2325-30. doi: 10.1073/pnas.0712162105. Epub 2008 Feb 19. Proc Natl Acad Sci U S A. 2008. PMID: 18287083 Free PMC article.
Old age and the hepatic sinusoid.
Le Couteur DG, Warren A, Cogger VC, Smedsrød B, Sørensen KK, De Cabo R, Fraser R, McCuskey RS. Le Couteur DG, et al. Among authors: de cabo r. Anat Rec (Hoboken). 2008 Jun;291(6):672-83. doi: 10.1002/ar.20661. Anat Rec (Hoboken). 2008. PMID: 18484614 Free article. Review.
Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span.
Pearson KJ, Baur JA, Lewis KN, Peshkin L, Price NL, Labinskyy N, Swindell WR, Kamara D, Minor RK, Perez E, Jamieson HA, Zhang Y, Dunn SR, Sharma K, Pleshko N, Woollett LA, Csiszar A, Ikeno Y, Le Couteur D, Elliott PJ, Becker KG, Navas P, Ingram DK, Wolf NS, Ungvari Z, Sinclair DA, de Cabo R. Pearson KJ, et al. Among authors: de cabo r. Cell Metab. 2008 Aug;8(2):157-68. doi: 10.1016/j.cmet.2008.06.011. Epub 2008 Jul 3. Cell Metab. 2008. PMID: 18599363 Free PMC article.
Determinants of serum-induced SIRT1 expression in older men: the CHAMP study.
Le Couteur DG, Benson VL, McMahon AC, Blyth F, Handelsman DJ, Seibel MJ, Kennerson M, Naganathan V, Cumming RG, de Cabo R. Le Couteur DG, et al. Among authors: de cabo r. J Gerontol A Biol Sci Med Sci. 2011 Jan;66(1):3-8. doi: 10.1093/gerona/glq158. Epub 2010 Sep 5. J Gerontol A Biol Sci Med Sci. 2011. PMID: 20819794 Free PMC article.
Aging biology and novel targets for drug discovery.
Le Couteur DG, McLachlan AJ, Quinn RJ, Simpson SJ, de Cabo R. Le Couteur DG, et al. Among authors: de cabo r. J Gerontol A Biol Sci Med Sci. 2012 Feb;67(2):168-74. doi: 10.1093/gerona/glr095. Epub 2011 Jun 21. J Gerontol A Biol Sci Med Sci. 2012. PMID: 21693687 Free PMC article. Review.
367 results