Reinheckel T - Search Results

1

Conditional Gene Targeting Reveals Cell Type-Specific Roles of the Lysosomal Protease Cathepsin L in Mammary Tumor Progression.

Parigiani MA, Ketscher A, Timme S, Bronsert P, Schlimpert M, Kammerer B, Jacquel A, Chaintreuil P, Reinheckel T. Parigiani MA, et al. Among authors: reinheckel t. Cancers (Basel). 2020 Jul 22;12(8):2004. doi: 10.3390/cancers12082004. Cancers (Basel). 2020. PMID: 32707827 Free PMC article.

2

Deficiency for the cysteine protease cathepsin L promotes tumor progression in mouse epidermis.

Dennemärker J, Lohmüller T, Mayerle J, Tacke M, Lerch MM, Coussens LM, Peters C, Reinheckel T. Dennemärker J, et al. Among authors: reinheckel t. Oncogene. 2010 Mar 18;29(11):1611-21. doi: 10.1038/onc.2009.466. Epub 2009 Dec 21. Oncogene. 2010. PMID: 20023699 Free PMC article.

3

Double deficiency of cathepsins B and L results in massive secretome alterations and suggests a degradative cathepsin-MMP axis.

Tholen S, Biniossek ML, Gansz M, Ahrens TD, Schlimpert M, Kizhakkedathu JN, Reinheckel T, Schilling O. Tholen S, et al. Among authors: reinheckel t. Cell Mol Life Sci. 2014 Mar;71(5):899-916. doi: 10.1007/s00018-013-1406-1. Epub 2013 Jun 29. Cell Mol Life Sci. 2014. PMID: 23811845 Free PMC article.

4

STAT3 expression, activity and functional consequences of STAT3 inhibition in esophageal squamous cell carcinomas and Barrett's adenocarcinomas.

Timme S, Ihde S, Fichter CD, Waehle V, Bogatyreva L, Atanasov K, Kohler I, Schöpflin A, Geddert H, Faller G, Klimstra D, Tang L, Reinheckel T, Hauschke D, Busch H, Boerries M, Werner M, Lassmann S. Timme S, et al. Among authors: reinheckel t. Oncogene. 2014 Jun 19;33(25):3256-66. doi: 10.1038/onc.2013.298. Epub 2013 Aug 5. Oncogene. 2014. PMID: 23912451

5

Stress-resistant Translation of Cathepsin L mRNA in Breast Cancer Progression.

Tholen M, Wolanski J, Stolze B, Chiabudini M, Gajda M, Bronsert P, Stickeler E, Rospert S, Reinheckel T. Tholen M, et al. Among authors: reinheckel t. J Biol Chem. 2015 Jun 19;290(25):15758-15769. doi: 10.1074/jbc.M114.624353. Epub 2015 May 8. J Biol Chem. 2015. PMID: 25957406 Free PMC article.

6

Neuroectoderm-specific deletion of cathepsin D in mice models human inherited neuronal ceroid lipofuscinosis type 10.

Ketscher A, Ketterer S, Dollwet-Mack S, Reif U, Reinheckel T. Ketscher A, et al. Among authors: reinheckel t. Biochimie. 2016 Mar;122:219-26. doi: 10.1016/j.biochi.2015.07.020. Epub 2015 Jul 29. Biochimie. 2016. PMID: 26232697

7

Inherited diseases caused by mutations in cathepsin protease genes.

Ketterer S, Gomez-Auli A, Hillebrand LE, Petrera A, Ketscher A, Reinheckel T. Ketterer S, et al. Among authors: reinheckel t. FEBS J. 2017 May;284(10):1437-1454. doi: 10.1111/febs.13980. Epub 2017 Jan 12. FEBS J. 2017. PMID: 27926992 Free article. Review.

8

Tumor cell- and microenvironment-specific roles of cysteine cathepsins in mouse models of human cancers.

Hölzen L, Parigiani MA, Reinheckel T. Hölzen L, et al. Among authors: reinheckel t. Biochim Biophys Acta Proteins Proteom. 2020 Jul;1868(7):140423. doi: 10.1016/j.bbapap.2020.140423. Epub 2020 Apr 2. Biochim Biophys Acta Proteins Proteom. 2020. PMID: 32247787 Review.

9

Cathepsin D deficiency in mammary epithelium transiently stalls breast cancer by interference with mTORC1 signaling.

Ketterer S, Mitschke J, Ketscher A, Schlimpert M, Reichardt W, Baeuerle N, Hess ME, Metzger P, Boerries M, Peters C, Kammerer B, Brummer T, Steinberg F, Reinheckel T. Ketterer S, et al. Among authors: reinheckel t. Nat Commun. 2020 Oct 12;11(1):5133. doi: 10.1038/s41467-020-18935-2. Nat Commun. 2020. PMID: 33046706 Free PMC article.

10

The lysosomal cysteine protease cathepsin L regulates keratinocyte proliferation by control of growth factor recycling.

Reinheckel T, Hagemann S, Dollwet-Mack S, Martinez E, Lohmüller T, Zlatkovic G, Tobin DJ, Maas-Szabowski N, Peters C. Reinheckel T, et al. J Cell Sci. 2005 Aug 1;118(Pt 15):3387-95. doi: 10.1242/jcs.02469. J Cell Sci. 2005. PMID: 16079282

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