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Microneedles for intradermal and transdermal drug delivery.
Tuan-Mahmood TM, McCrudden MT, Torrisi BM, McAlister E, Garland MJ, Singh TR, Donnelly RF. Tuan-Mahmood TM, et al. Eur J Pharm Sci. 2013 Dec 18;50(5):623-37. doi: 10.1016/j.ejps.2013.05.005. Epub 2013 May 13. Eur J Pharm Sci. 2013. PMID: 23680534 Free PMC article. Review.
Hydrogel-forming microneedles prepared from "super swelling" polymers combined with lyophilised wafers for transdermal drug delivery.
Donnelly RF, McCrudden MT, Zaid Alkilani A, Larrañeta E, McAlister E, Courtenay AJ, Kearney MC, Singh TR, McCarthy HO, Kett VL, Caffarel-Salvador E, Al-Zahrani S, Woolfson AD. Donnelly RF, et al. PLoS One. 2014 Oct 31;9(10):e111547. doi: 10.1371/journal.pone.0111547. eCollection 2014. PLoS One. 2014. PMID: 25360806 Free PMC article.
Repeat application of microneedles does not alter skin appearance or barrier function and causes no measurable disturbance of serum biomarkers of infection, inflammation or immunity in mice in vivo.
Vicente-Perez EM, Larrañeta E, McCrudden MTC, Kissenpfennig A, Hegarty S, McCarthy HO, Donnelly RF. Vicente-Perez EM, et al. Among authors: mccrudden mtc. Eur J Pharm Biopharm. 2017 Aug;117:400-407. doi: 10.1016/j.ejpb.2017.04.029. Epub 2017 May 3. Eur J Pharm Biopharm. 2017. PMID: 28478160 Free PMC article.
Transdermal delivery of gentamicin using dissolving microneedle arrays for potential treatment of neonatal sepsis.
González-Vázquez P, Larrañeta E, McCrudden MTC, Jarrahian C, Rein-Weston A, Quintanar-Solares M, Zehrung D, McCarthy H, Courtenay AJ, Donnelly RF. González-Vázquez P, et al. Among authors: mccrudden mtc. J Control Release. 2017 Nov 10;265:30-40. doi: 10.1016/j.jconrel.2017.07.032. Epub 2017 Jul 25. J Control Release. 2017. PMID: 28754611 Free PMC article.
Microneedle-Mediated Transdermal Delivery of Bevacizumab.
Courtenay AJ, McCrudden MTC, McAvoy KJ, McCarthy HO, Donnelly RF. Courtenay AJ, et al. Among authors: mccrudden mtc. Mol Pharm. 2018 Aug 6;15(8):3545-3556. doi: 10.1021/acs.molpharmaceut.8b00544. Epub 2018 Jul 24. Mol Pharm. 2018. PMID: 29996645
48 results