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Spatial Transcriptomics and In Situ Sequencing to Study Alzheimer's Disease.
Chen WT, Lu A, Craessaerts K, Pavie B, Sala Frigerio C, Corthout N, Qian X, Laláková J, Kühnemund M, Voytyuk I, Wolfs L, Mancuso R, Salta E, Balusu S, Snellinx A, Munck S, Jurek A, Fernandez Navarro J, Saido TC, Huitinga I, Lundeberg J, Fiers M, De Strooper B. Chen WT, et al. Among authors: huitinga i. Cell. 2020 Aug 20;182(4):976-991.e19. doi: 10.1016/j.cell.2020.06.038. Epub 2020 Jul 22. Cell. 2020. PMID: 32702314 Free article.
The microtubule regulator stathmin is an endogenous protein agonist for TLR3.
Bsibsi M, Bajramovic JJ, Vogt MH, van Duijvenvoorden E, Baghat A, Persoon-Deen C, Tielen F, Verbeek R, Huitinga I, Ryffel B, Kros A, Gerritsen WH, Amor S, van Noort JM. Bsibsi M, et al. Among authors: huitinga i. J Immunol. 2010 Jun 15;184(12):6929-37. doi: 10.4049/jimmunol.0902419. Epub 2010 May 12. J Immunol. 2010. PMID: 20483774
LifeTime and improving European healthcare through cell-based interceptive medicine.
Rajewsky N, Almouzni G, Gorski SA, Aerts S, Amit I, Bertero MG, Bock C, Bredenoord AL, Cavalli G, Chiocca S, Clevers H, De Strooper B, Eggert A, Ellenberg J, Fernández XM, Figlerowicz M, Gasser SM, Hubner N, Kjems J, Knoblich JA, Krabbe G, Lichter P, Linnarsson S, Marine JC, Marioni JC, Marti-Renom MA, Netea MG, Nickel D, Nollmann M, Novak HR, Parkinson H, Piccolo S, Pinheiro I, Pombo A, Popp C, Reik W, Roman-Roman S, Rosenstiel P, Schultze JL, Stegle O, Tanay A, Testa G, Thanos D, Theis FJ, Torres-Padilla ME, Valencia A, Vallot C, van Oudenaarden A, Vidal M, Voet T; LifeTime Community Working Groups. Rajewsky N, et al. Nature. 2020 Nov;587(7834):377-386. doi: 10.1038/s41586-020-2715-9. Epub 2020 Sep 7. Nature. 2020. PMID: 32894860 Free PMC article.
Gene-expression profiling of individuals resilient to Alzheimer's disease reveals higher expression of genes related to metallothionein and mitochondrial processes and no changes in the unfolded protein response.
de Vries LE, Jongejan A, Monteiro Fortes J, Balesar R, Rozemuller AJM, Moerland PD, Huitinga I, Swaab DF, Verhaagen J. de Vries LE, et al. Among authors: huitinga i. Acta Neuropathol Commun. 2024 Apr 25;12(1):68. doi: 10.1186/s40478-024-01760-9. Acta Neuropathol Commun. 2024. PMID: 38664739 Free PMC article.
Restoring immune suppression in the multiple sclerosis brain.
Koning N, Uitdehaag BM, Huitinga I, Hoek RM. Koning N, et al. Among authors: huitinga i. Prog Neurobiol. 2009 Dec;89(4):359-68. doi: 10.1016/j.pneurobio.2009.09.005. Epub 2009 Oct 1. Prog Neurobiol. 2009. PMID: 19800386 Review.
138 results