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Drug targeting CYP2E1 for the treatment of early-stage alcoholic steatohepatitis.
Diesinger T, Buko V, Lautwein A, Dvorsky R, Belonovskaya E, Lukivskaya O, Naruta E, Kirko S, Andreev V, Buckert D, Bergler S, Renz C, Schneider E, Kuchenbauer F, Kumar M, Günes C, Büchele B, Simmet T, Müller-Enoch D, Wirth T, Haehner T. Diesinger T, et al. Among authors: dvorsky r. PLoS One. 2020 Jul 23;15(7):e0235990. doi: 10.1371/journal.pone.0235990. eCollection 2020. PLoS One. 2020. PMID: 32701948 Free PMC article.
A New CYP2E1 Inhibitor, 12-Imidazolyl-1-dodecanol, Represents a Potential Treatment for Hepatocellular Carcinoma.
Diesinger T, Lautwein A, Bergler S, Buckert D, Renz C, Dvorsky R, Buko V, Kirko S, Schneider E, Kuchenbauer F, Kumar M, Günes C, Genze F, Büchele B, Simmet T, Haslbeck M, Masur K, Barth T, Müller-Enoch D, Wirth T, Haehner T. Diesinger T, et al. Among authors: dvorsky r. Can J Gastroenterol Hepatol. 2021 Feb 2;2021:8854432. doi: 10.1155/2021/8854432. eCollection 2021. Can J Gastroenterol Hepatol. 2021. PMID: 33604316 Free PMC article.
CD28-dependent Rac1 activation is the molecular target of azathioprine in primary human CD4+ T lymphocytes.
Tiede I, Fritz G, Strand S, Poppe D, Dvorsky R, Strand D, Lehr HA, Wirtz S, Becker C, Atreya R, Mudter J, Hildner K, Bartsch B, Holtmann M, Blumberg R, Walczak H, Iven H, Galle PR, Ahmadian MR, Neurath MF. Tiede I, et al. Among authors: dvorsky r. J Clin Invest. 2003 Apr;111(8):1133-45. doi: 10.1172/JCI16432. J Clin Invest. 2003. PMID: 12697733 Free PMC article.
Alternative splicing of Rac1 generates Rac1b, a self-activating GTPase.
Fiegen D, Haeusler LC, Blumenstein L, Herbrand U, Dvorsky R, Vetter IR, Ahmadian MR. Fiegen D, et al. Among authors: dvorsky r. J Biol Chem. 2004 Feb 6;279(6):4743-9. doi: 10.1074/jbc.M310281200. Epub 2003 Nov 18. J Biol Chem. 2004. PMID: 14625275 Free article.
Comparative functional analysis of the Rac GTPases.
Haeusler LC, Blumenstein L, Stege P, Dvorsky R, Ahmadian MR. Haeusler LC, et al. Among authors: dvorsky r. FEBS Lett. 2003 Dec 18;555(3):556-60. doi: 10.1016/s0014-5793(03)01351-6. FEBS Lett. 2003. PMID: 14675773 Free article.
71 results