Molenaar P - Search Results

1

Sarcoplasmic reticulum calcium mishandling: central tenet in heart failure?

Denniss AL, Dashwood AM, Molenaar P, Beard NA. Denniss AL, et al. Among authors: molenaar p. Biophys Rev. 2020 Aug;12(4):865-878. doi: 10.1007/s12551-020-00736-y. Epub 2020 Jul 22. Biophys Rev. 2020. PMID: 32696300 Free PMC article. Review.

2

Ryanodine receptor modification and regulation by intracellular Ca²⁺ and Mg²⁺ in healthy and failing human hearts.

Walweel K, Molenaar P, Imtiaz MS, Denniss A, Dos Remedios C, van Helden DF, Dulhunty AF, Laver DR, Beard NA. Walweel K, et al. Among authors: molenaar p. J Mol Cell Cardiol. 2017 Mar;104:53-62. doi: 10.1016/j.yjmcc.2017.01.016. Epub 2017 Jan 26. J Mol Cell Cardiol. 2017. PMID: 28131631

3

Effects of omecamtiv mecarbil on failing human ventricular trabeculae and interaction with (-)-noradrenaline.

Dashwood A, Cheesman E, Wong YW, Haqqani H, Beard N, Hay K, Spratt M, Chan W, Molenaar P. Dashwood A, et al. Among authors: molenaar p. Pharmacol Res Perspect. 2021 May;9(3):e00760. doi: 10.1002/prp2.760. Pharmacol Res Perspect. 2021. PMID: 33929079 Free PMC article.

4

Understanding How Phosphorylation and Redox Modifications Regulate Cardiac Ryanodine Receptor Type 2 Activity to Produce an Arrhythmogenic Phenotype in Advanced Heart Failure.

Dashwood A, Cheesman E, Beard N, Haqqani H, Wong YW, Molenaar P. Dashwood A, et al. Among authors: molenaar p. ACS Pharmacol Transl Sci. 2020 Jun 1;3(4):563-582. doi: 10.1021/acsptsci.0c00003. eCollection 2020 Aug 14. ACS Pharmacol Transl Sci. 2020. PMID: 32832863 Free PMC article. Review.

5

Differences in the regulation of RyR2 from human, sheep, and rat by Ca²⁺ and Mg²⁺ in the cytoplasm and in the lumen of the sarcoplasmic reticulum.

Walweel K, Li J, Molenaar P, Imtiaz MS, Quail A, dos Remedios CG, Beard NA, Dulhunty AF, van Helden DF, Laver DR. Walweel K, et al. Among authors: molenaar p. J Gen Physiol. 2014 Sep;144(3):263-71. doi: 10.1085/jgp.201311157. J Gen Physiol. 2014. PMID: 25156119 Free PMC article.

6

Calmodulin inhibition of human RyR2 channels requires phosphorylation of RyR2-S2808 or RyR2-S2814.

Walweel K, Gomez-Hurtado N, Rebbeck RT, Oo YW, Beard NA, Molenaar P, Dos Remedios C, van Helden DF, Cornea RL, Knollmann BC, Laver DR. Walweel K, et al. Among authors: molenaar p. J Mol Cell Cardiol. 2019 May;130:96-106. doi: 10.1016/j.yjmcc.2019.03.018. Epub 2019 Mar 27. J Mol Cell Cardiol. 2019. PMID: 30928430 Free PMC article.

7

Correction to "Understanding How Phosphorylation and Redox Modifications Regulate Cardiac Ryanodine Receptor Type 2 Activity to Produce an Arrhythmogenic Phenotype in Advanced Heart Failure".

Dashwood A, Beard N, Wong YW, Haqqani H, Cheesman E, Molenaar P. Dashwood A, et al. Among authors: molenaar p. ACS Pharmacol Transl Sci. 2020 Oct 19;3(6):1422. doi: 10.1021/acsptsci.0c00148. eCollection 2020 Dec 11. ACS Pharmacol Transl Sci. 2020. PMID: 33344910 Free PMC article.

8

G protein-coupled receptors in cardiac biology: old and new receptors.

Foster SR, Roura E, Molenaar P, Thomas WG. Foster SR, et al. Among authors: molenaar p. Biophys Rev. 2015 Mar;7(1):77-89. doi: 10.1007/s12551-014-0154-2. Epub 2015 Jan 13. Biophys Rev. 2015. PMID: 28509979 Free PMC article.

9

Phenytoin Reduces Activity of Cardiac Ryanodine Receptor 2; A Potential Mechanism for Its Cardioprotective Action.

Ashna A, van Helden DF, Dos Remedios C, Molenaar P, Laver DR. Ashna A, et al. Among authors: molenaar p. Mol Pharmacol. 2020 Apr;97(4):250-258. doi: 10.1124/mol.119.117721. Epub 2020 Feb 3. Mol Pharmacol. 2020. PMID: 32015008

10

Cardiostimulant effects of urotensin-II in human heart in vitro.

Russell FD, Molenaar P, O'Brien DM. Russell FD, et al. Among authors: molenaar p. Br J Pharmacol. 2001 Jan;132(1):5-9. doi: 10.1038/sj.bjp.0703811. Br J Pharmacol. 2001. PMID: 11156554 Free PMC article.

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