Summers SA - Search Results

1

Summers SA, Chaurasia B, Holland WL. Summers SA, et al. Nat Metab. 2019 Nov;1(11):1051-1058. doi: 10.1038/s42255-019-0134-8. Epub 2019 Oct 24. Nat Metab. 2019. PMID: 32694860 Free PMC article. Review.

2

A role for sphingolipids in producing the common features of type 2 diabetes, metabolic syndrome X, and Cushing's syndrome.

Summers SA, Nelson DH. Summers SA, et al. Diabetes. 2005 Mar;54(3):591-602. doi: 10.2337/diabetes.54.3.591. Diabetes. 2005. PMID: 15734832 Review.

3

Acid ceramidase overexpression prevents the inhibitory effects of saturated fatty acids on insulin signaling.

Chavez JA, Holland WL, Bär J, Sandhoff K, Summers SA. Chavez JA, et al. Among authors: summers sa. J Biol Chem. 2005 May 20;280(20):20148-53. doi: 10.1074/jbc.M412769200. Epub 2005 Mar 17. J Biol Chem. 2005. PMID: 15774472 Free article.

4

Ceramides in insulin resistance and lipotoxicity.

Summers SA. Summers SA. Prog Lipid Res. 2006 Jan;45(1):42-72. doi: 10.1016/j.plipres.2005.11.002. Epub 2005 Dec 19. Prog Lipid Res. 2006. PMID: 16445986 Review.

5

Inhibition of ceramide synthesis ameliorates glucocorticoid-, saturated-fat-, and obesity-induced insulin resistance.

Holland WL, Brozinick JT, Wang LP, Hawkins ED, Sargent KM, Liu Y, Narra K, Hoehn KL, Knotts TA, Siesky A, Nelson DH, Karathanasis SK, Fontenot GK, Birnbaum MJ, Summers SA. Holland WL, et al. Among authors: summers sa. Cell Metab. 2007 Mar;5(3):167-79. doi: 10.1016/j.cmet.2007.01.002. Cell Metab. 2007. PMID: 17339025 Free article.

6

Lipid mediators of insulin resistance.

Holland WL, Knotts TA, Chavez JA, Wang LP, Hoehn KL, Summers SA. Holland WL, et al. Among authors: summers sa. Nutr Rev. 2007 Jun;65(6 Pt 2):S39-46. doi: 10.1111/j.1753-4887.2007.tb00327.x. Nutr Rev. 2007. PMID: 17605313 Review.

7

Sphingolipids, insulin resistance, and metabolic disease: new insights from in vivo manipulation of sphingolipid metabolism.

Holland WL, Summers SA. Holland WL, et al. Among authors: summers sa. Endocr Rev. 2008 Jun;29(4):381-402. doi: 10.1210/er.2007-0025. Epub 2008 May 1. Endocr Rev. 2008. PMID: 18451260 Free PMC article. Review.

8

Ablation of AMP-activated protein kinase alpha2 activity exacerbates insulin resistance induced by high-fat feeding of mice.

Fujii N, Ho RC, Manabe Y, Jessen N, Toyoda T, Holland WL, Summers SA, Hirshman MF, Goodyear LJ. Fujii N, et al. Among authors: summers sa. Diabetes. 2008 Nov;57(11):2958-66. doi: 10.2337/db07-1187. Epub 2008 Aug 26. Diabetes. 2008. PMID: 18728234 Free PMC article.

9

Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin.

Holland WL, Miller RA, Wang ZV, Sun K, Barth BM, Bui HH, Davis KE, Bikman BT, Halberg N, Rutkowski JM, Wade MR, Tenorio VM, Kuo MS, Brozinick JT, Zhang BB, Birnbaum MJ, Summers SA, Scherer PE. Holland WL, et al. Among authors: summers sa. Nat Med. 2011 Jan;17(1):55-63. doi: 10.1038/nm.2277. Epub 2010 Dec 26. Nat Med. 2011. PMID: 21186369 Free PMC article.

10

Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid-induced ceramide biosynthesis in mice.

Holland WL, Bikman BT, Wang LP, Yuguang G, Sargent KM, Bulchand S, Knotts TA, Shui G, Clegg DJ, Wenk MR, Pagliassotti MJ, Scherer PE, Summers SA. Holland WL, et al. Among authors: summers sa. J Clin Invest. 2011 May;121(5):1858-70. doi: 10.1172/JCI43378. Epub 2011 Apr 1. J Clin Invest. 2011. PMID: 21490391 Free PMC article.

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