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Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.
Aregger M, Lawson KA, Billmann M, Costanzo M, Tong AHY, Chan K, Rahman M, Brown KR, Ross C, Usaj M, Nedyalkova L, Sizova O, Habsid A, Pawling J, Lin ZY, Abdouni H, Wong CJ, Weiss A, Mero P, Dennis JW, Gingras AC, Myers CL, Andrews BJ, Boone C, Moffat J. Aregger M, et al. Among authors: pawling j. Nat Metab. 2020 Jun;2(6):499-513. doi: 10.1038/s42255-020-0211-z. Epub 2020 Jun 1. Nat Metab. 2020. PMID: 32694731 Free PMC article.
alpha 2-HS glycoprotein/fetuin, a transforming growth factor-beta/bone morphogenetic protein antagonist, regulates postnatal bone growth and remodeling.
Szweras M, Liu D, Partridge EA, Pawling J, Sukhu B, Clokie C, Jahnen-Dechent W, Tenenbaum HC, Swallow CJ, Grynpas MD, Dennis JW. Szweras M, et al. Among authors: pawling j. J Biol Chem. 2002 May 31;277(22):19991-7. doi: 10.1074/jbc.M112234200. Epub 2002 Mar 18. J Biol Chem. 2002. PMID: 11901155 Free article.
Complex N-glycan and metabolic control in tumor cells.
Mendelsohn R, Cheung P, Berger L, Partridge E, Lau K, Datti A, Pawling J, Dennis JW. Mendelsohn R, et al. Among authors: pawling j. Cancer Res. 2007 Oct 15;67(20):9771-80. doi: 10.1158/0008-5472.CAN-06-4580. Cancer Res. 2007. PMID: 17942907
The adaptor protein p66Shc inhibits mTOR-dependent anabolic metabolism.
Soliman MA, Abdel Rahman AM, Lamming DW, Birsoy K, Pawling J, Frigolet ME, Lu H, Fantus IG, Pasculescu A, Zheng Y, Sabatini DM, Dennis JW, Pawson T. Soliman MA, et al. Among authors: pawling j. Sci Signal. 2014 Feb 18;7(313):ra17. doi: 10.1126/scisignal.2004785. Sci Signal. 2014. PMID: 24550542 Free PMC article.
42 results