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Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.
Aregger M, Lawson KA, Billmann M, Costanzo M, Tong AHY, Chan K, Rahman M, Brown KR, Ross C, Usaj M, Nedyalkova L, Sizova O, Habsid A, Pawling J, Lin ZY, Abdouni H, Wong CJ, Weiss A, Mero P, Dennis JW, Gingras AC, Myers CL, Andrews BJ, Boone C, Moffat J. Aregger M, et al. Among authors: gingras ac. Nat Metab. 2020 Jun;2(6):499-513. doi: 10.1038/s42255-020-0211-z. Epub 2020 Jun 1. Nat Metab. 2020. PMID: 32694731 Free PMC article.
The genetic landscape of a cell.
Costanzo M, Baryshnikova A, Bellay J, Kim Y, Spear ED, Sevier CS, Ding H, Koh JL, Toufighi K, Mostafavi S, Prinz J, St Onge RP, VanderSluis B, Makhnevych T, Vizeacoumar FJ, Alizadeh S, Bahr S, Brost RL, Chen Y, Cokol M, Deshpande R, Li Z, Lin ZY, Liang W, Marback M, Paw J, San Luis BJ, Shuteriqi E, Tong AH, van Dyk N, Wallace IM, Whitney JA, Weirauch MT, Zhong G, Zhu H, Houry WA, Brudno M, Ragibizadeh S, Papp B, Pál C, Roth FP, Giaever G, Nislow C, Troyanskaya OG, Bussey H, Bader GD, Gingras AC, Morris QD, Kim PM, Kaiser CA, Myers CL, Andrews BJ, Boone C. Costanzo M, et al. Among authors: gingras ac. Science. 2010 Jan 22;327(5964):425-31. doi: 10.1126/science.1180823. Science. 2010. PMID: 20093466 Free PMC article.
A lentiviral functional proteomics approach identifies chromatin remodeling complexes important for the induction of pluripotency.
Mak AB, Ni Z, Hewel JA, Chen GI, Zhong G, Karamboulas K, Blakely K, Smiley S, Marcon E, Roudeva D, Li J, Olsen JB, Wan C, Punna T, Isserlin R, Chetyrkin S, Gingras AC, Emili A, Greenblatt J, Moffat J. Mak AB, et al. Among authors: gingras ac. Mol Cell Proteomics. 2010 May;9(5):811-23. doi: 10.1074/mcp.M000002-MCP201. Epub 2010 Mar 19. Mol Cell Proteomics. 2010. PMID: 20305087 Free PMC article.
Quantitative analysis of fitness and genetic interactions in yeast on a genome scale.
Baryshnikova A, Costanzo M, Kim Y, Ding H, Koh J, Toufighi K, Youn JY, Ou J, San Luis BJ, Bandyopadhyay S, Hibbs M, Hess D, Gingras AC, Bader GD, Troyanskaya OG, Brown GW, Andrews B, Boone C, Myers CL. Baryshnikova A, et al. Among authors: gingras ac. Nat Methods. 2010 Dec;7(12):1017-24. doi: 10.1038/nmeth.1534. Epub 2010 Nov 14. Nat Methods. 2010. PMID: 21076421 Free PMC article.
SAINT: probabilistic scoring of affinity purification-mass spectrometry data.
Choi H, Larsen B, Lin ZY, Breitkreutz A, Mellacheruvu D, Fermin D, Qin ZS, Tyers M, Gingras AC, Nesvizhskii AI. Choi H, et al. Among authors: gingras ac. Nat Methods. 2011 Jan;8(1):70-3. doi: 10.1038/nmeth.1541. Epub 2010 Dec 5. Nat Methods. 2011. PMID: 21131968 Free PMC article.
Systematic exploration of essential yeast gene function with temperature-sensitive mutants.
Li Z, Vizeacoumar FJ, Bahr S, Li J, Warringer J, Vizeacoumar FS, Min R, Vandersluis B, Bellay J, Devit M, Fleming JA, Stephens A, Haase J, Lin ZY, Baryshnikova A, Lu H, Yan Z, Jin K, Barker S, Datti A, Giaever G, Nislow C, Bulawa C, Myers CL, Costanzo M, Gingras AC, Zhang Z, Blomberg A, Bloom K, Andrews B, Boone C. Li Z, et al. Among authors: gingras ac. Nat Biotechnol. 2011 Apr;29(4):361-7. doi: 10.1038/nbt.1832. Epub 2011 Mar 27. Nat Biotechnol. 2011. PMID: 21441928 Free PMC article.
Global gene deletion analysis exploring yeast filamentous growth.
Ryan O, Shapiro RS, Kurat CF, Mayhew D, Baryshnikova A, Chin B, Lin ZY, Cox MJ, Vizeacoumar F, Cheung D, Bahr S, Tsui K, Tebbji F, Sellam A, Istel F, Schwarzmüller T, Reynolds TB, Kuchler K, Gifford DK, Whiteway M, Giaever G, Nislow C, Costanzo M, Gingras AC, Mitra RD, Andrews B, Fink GR, Cowen LE, Boone C. Ryan O, et al. Among authors: gingras ac. Science. 2012 Sep 14;337(6100):1353-6. doi: 10.1126/science.1224339. Science. 2012. PMID: 22984072
Temporal regulation of EGF signalling networks by the scaffold protein Shc1.
Zheng Y, Zhang C, Croucher DR, Soliman MA, St-Denis N, Pasculescu A, Taylor L, Tate SA, Hardy WR, Colwill K, Dai AY, Bagshaw R, Dennis JW, Gingras AC, Daly RJ, Pawson T. Zheng Y, et al. Among authors: gingras ac. Nature. 2013 Jul 11;499(7457):166-71. doi: 10.1038/nature12308. Nature. 2013. PMID: 23846654 Free PMC article.
375 results