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CPX-351 Pharmacokinetics and Safety in Adults with Hematologic Malignancies and Renal Function Impairment: Phase 1 Trial.
Solomon SR, Powell BL, Koprivnikar J, Lai C, Male H, Michaelis LC, Newell LF, Sanford D, Jenkins J, Zelaya A, Coppola S, Faderl S, Walter RB. Solomon SR, et al. Cancers (Basel). 2024 Feb 24;16(5):915. doi: 10.3390/cancers16050915. Cancers (Basel). 2024. PMID: 38473278 Free PMC article.
The primary objective was to assess the PK parameters for cytarabine, daunorubicin, and their respective metabolites, arabinosyluracil (Ara-U) and daunorubicinol. Renal impairment did not significantly impact the cytarabine, daunorubicin, or daunorubicinol exposure, …
The primary objective was to assess the PK parameters for cytarabine, daunorubicin, and their respective metabolites, arabinosyluracil (A
Knowledge, attitudes, and practices of Anopheles mosquito control through insecticide treated nets and community-based health programs to prevent malaria in East Sumba Island, Indonesia.
Bandzuh JT, Ernst KC, Gunn JKL, Pandarangga S, Yowi LRK, Hobgen S, Cavanaugh KR, Kalaway RY, Kalunga NRJ, Killa MF, Ara UH, Uejio CK, Hayden MH. Bandzuh JT, et al. PLOS Glob Public Health. 2022 Sep 2;2(9):e0000241. doi: 10.1371/journal.pgph.0000241. eCollection 2022. PLOS Glob Public Health. 2022. PMID: 36962713 Free PMC article.
Exploring Solvent Effects in the Radiosynthesis of 18F-Labeled Thymidine Analogues toward Clinical Translation for Positron Emission Tomography Imaging.
Li J, Van Valkenburgh J, Conti PS, Chen K. Li J, et al. ACS Pharmacol Transl Sci. 2020 Dec 4;4(1):266-275. doi: 10.1021/acsptsci.0c00184. eCollection 2021 Feb 12. ACS Pharmacol Transl Sci. 2020. PMID: 33615178 Free PMC article.
Thymidine analogues, 5-substituted 2'-deoxy-2'-[(18)F]fluoro-arabinofuranosyluracil derivatives, are promising positron emission tomography (PET) tracers being evaluated for noninvasive imaging of cancer cell proliferation and/or reporter gene expression. We report the rad …
Thymidine analogues, 5-substituted 2'-deoxy-2'-[(18)F]fluoro-arabinofuranosyluracil derivatives, are promising positron emission tomo …
Anion exchange resins in phosphate form as versatile carriers for the reactions catalyzed by nucleoside phosphorylases.
Artsemyeva JN, Remeeva EA, Buravskaya TN, Konstantinova ID, Esipov RS, Miroshnikov AI, Litvinko NM, Mikhailopulo IA. Artsemyeva JN, et al. Beilstein J Org Chem. 2020 Oct 22;16:2607-2622. doi: 10.3762/bjoc.16.212. eCollection 2020. Beilstein J Org Chem. 2020. PMID: 33133292 Free PMC article.
In the present work, we suggested anion exchange resins in the phosphate form as a source of phosphate, one of the substrates of the phosphorolysis of uridine, thymidine, and 1-(beta-D-arabinofuranosyl)uracil (Ara-U) catalyzed by recombinant E. coli uridine (UP) and …
In the present work, we suggested anion exchange resins in the phosphate form as a source of phosphate, one of the substrates of the phospho …
731 results