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Exosomes originating from infection with the cytoplasmic single-stranded RNA virus Rift Valley fever virus (RVFV) protect recipient cells by inducing RIG-I mediated IFN-B response that leads to activation of autophagy.
Alem F, Olanrewaju AA, Omole S, Hobbs HE, Ahsan N, Matulis G, Brantner CA, Zhou W, Petricoin EF, Liotta LA, Caputi M, Bavari S, Wu Y, Kashanchi F, Hakami RM. Alem F, et al. Cell Biosci. 2021 Dec 25;11(1):220. doi: 10.1186/s13578-021-00732-z. Cell Biosci. 2021. PMID: 34953502 Free PMC article.
HSP90 is part of a protein complex with the L polymerase of Rift Valley fever phlebovirus and prevents its degradation by the proteasome during the viral genome replication/transcription stage.
Alem F, Brahms A, Tarasaki K, Omole S, Kehn-Hall K, Schmaljohn CS, Bavari S, Makino S, Hakami RM. Alem F, et al. Front Cell Infect Microbiol. 2024 May 10;14:1331755. doi: 10.3389/fcimb.2024.1331755. eCollection 2024. Front Cell Infect Microbiol. 2024. PMID: 38800833 Free PMC article.
Development of a hybrid alphavirus-SARS-CoV-2 pseudovirion for rapid quantification of neutralization antibodies and antiviral drugs.
Hetrick B, Chilin LD, He S, Dabbagh D, Alem F, Narayanan A, Luchini A, Li T, Liu X, Copeland J, Pak A, Cunningham T, Liotta L, Petricoin EF, Andalibi A, Wu Y. Hetrick B, et al. Among authors: alem f. Cell Rep Methods. 2022 Mar 28;2(3):100181. doi: 10.1016/j.crmeth.2022.100181. Epub 2022 Feb 24. Cell Rep Methods. 2022. PMID: 35229082 Free PMC article.
Brilacidin Demonstrates Inhibition of SARS-CoV-2 in Cell Culture.
Bakovic A, Risner K, Bhalla N, Alem F, Chang TL, Weston WK, Harness JA, Narayanan A. Bakovic A, et al. Among authors: alem f. Viruses. 2021 Feb 9;13(2):271. doi: 10.3390/v13020271. Viruses. 2021. PMID: 33572467 Free PMC article.
47 results