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Synthesis, structure-activity, and structure-stability relationships of 2-substituted-N-(4-oxo-3-oxetanyl) N-acylethanolamine acid amidase (NAAA) inhibitors.
Vitale R, Ottonello G, Petracca R, Bertozzi SM, Ponzano S, Armirotti A, Berteotti A, Dionisi M, Cavalli A, Piomelli D, Bandiera T, Bertozzi F. Vitale R, et al. Among authors: bertozzi f, bertozzi sm. ChemMedChem. 2014 Feb;9(2):323-36. doi: 10.1002/cmdc.201300416. Epub 2014 Jan 8. ChemMedChem. 2014. PMID: 24403170 Free article.
Structural determinants of peripheral O-arylcarbamate FAAH inhibitors render them dual substrates for Abcb1 and Abcg2 and restrict their access to the brain.
Moreno-Sanz G, Barrera B, Armirotti A, Bertozzi SM, Scarpelli R, Bandiera T, Prieto JG, Duranti A, Tarzia G, Merino G, Piomelli D. Moreno-Sanz G, et al. Among authors: bertozzi sm. Pharmacol Res. 2014 Sep;87:87-93. doi: 10.1016/j.phrs.2014.06.004. Epub 2014 Jun 30. Pharmacol Res. 2014. PMID: 24993496 Free PMC article.
3,4-Dihydro-1,3,5-triazin-2(1H)-ones as the First Dual BACE-1/GSK-3β Fragment Hits against Alzheimer's Disease.
Prati F, De Simone A, Armirotti A, Summa M, Pizzirani D, Scarpelli R, Bertozzi SM, Perez DI, Andrisano V, Perez-Castillo A, Monti B, Massenzio F, Polito L, Racchi M, Sabatino P, Bottegoni G, Martinez A, Cavalli A, Bolognesi ML. Prati F, et al. Among authors: bertozzi sm. ACS Chem Neurosci. 2015 Oct 21;6(10):1665-82. doi: 10.1021/acschemneuro.5b00121. Epub 2015 Aug 3. ACS Chem Neurosci. 2015. PMID: 26171616 Free article.
Kernel-Based, Partial Least Squares Quantitative Structure-Retention Relationship Model for UPLC Retention Time Prediction: A Useful Tool for Metabolite Identification.
Falchi F, Bertozzi SM, Ottonello G, Ruda GF, Colombano G, Fiorelli C, Martucci C, Bertorelli R, Scarpelli R, Cavalli A, Bandiera T, Armirotti A. Falchi F, et al. Among authors: bertozzi sm. Anal Chem. 2016 Oct 4;88(19):9510-9517. doi: 10.1021/acs.analchem.6b02075. Epub 2016 Sep 14. Anal Chem. 2016. PMID: 27583774 Free article.
Brain-wide Mapping of Endogenous Serotonergic Transmission via Chemogenetic fMRI.
Giorgi A, Migliarini S, Galbusera A, Maddaloni G, Mereu M, Margiani G, Gritti M, Landi S, Trovato F, Bertozzi SM, Armirotti A, Ratto GM, De Luca MA, Tonini R, Gozzi A, Pasqualetti M. Giorgi A, et al. Among authors: bertozzi sm. Cell Rep. 2017 Oct 24;21(4):910-918. doi: 10.1016/j.celrep.2017.09.087. Cell Rep. 2017. PMID: 29069598 Free article.
Identification of a 2,4-diaminopyrimidine scaffold targeting Trypanosoma brucei pteridine reductase 1 from the LIBRA compound library screening campaign.
Linciano P, Cullia G, Borsari C, Santucci M, Ferrari S, Witt G, Gul S, Kuzikov M, Ellinger B, Santarém N, Cordeiro da Silva A, Conti P, Bolognesi ML, Roberti M, Prati F, Bartoccini F, Retini M, Piersanti G, Cavalli A, Goldoni L, Bertozzi SM, Bertozzi F, Brambilla E, Rizzo V, Piomelli D, Pinto A, Bandiera T, Costi MP. Linciano P, et al. Among authors: bertozzi f, bertozzi sm. Eur J Med Chem. 2020 Mar 1;189:112047. doi: 10.1016/j.ejmech.2020.112047. Epub 2020 Jan 10. Eur J Med Chem. 2020. PMID: 31982652 Free article.
Design, Synthesis, Dynamic Docking, Biochemical Characterization, and in Vivo Pharmacokinetics Studies of Novel Topoisomerase II Poisons with Promising Antiproliferative Activity.
Arencibia JM, Brindani N, Franco-Ulloa S, Nigro M, Kuriappan JA, Ottonello G, Bertozzi SM, Summa M, Girotto S, Bertorelli R, Armirotti A, De Vivo M. Arencibia JM, et al. Among authors: bertozzi sm. J Med Chem. 2020 Apr 9;63(7):3508-3521. doi: 10.1021/acs.jmedchem.9b01760. Epub 2020 Mar 30. J Med Chem. 2020. PMID: 32196342 Free PMC article.
118 results