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Page 1
Lactate released by inflammatory bone marrow neutrophils induces their mobilization via endothelial GPR81 signaling.
Khatib-Massalha E, Bhattacharya S, Massalha H, Biram A, Golan K, Kollet O, Kumari A, Avemaria F, Petrovich-Kopitman E, Gur-Cohen S, Itkin T, Brandenburger I, Spiegel A, Shulman Z, Gerhart-Hines Z, Itzkovitz S, Gunzer M, Offermanns S, Alon R, Ariel A, Lapidot T. Khatib-Massalha E, et al. Nat Commun. 2020 Jul 15;11(1):3547. doi: 10.1038/s41467-020-17402-2. Nat Commun. 2020. PMID: 32669546 Free PMC article.
Histone deacetylase 3 prepares brown adipose tissue for acute thermogenic challenge.
Emmett MJ, Lim HW, Jager J, Richter HJ, Adlanmerini M, Peed LC, Briggs ER, Steger DJ, Ma T, Sims CA, Baur JA, Pei L, Won KJ, Seale P, Gerhart-Hines Z, Lazar MA. Emmett MJ, et al. Nature. 2017 Jun 22;546(7659):544-548. doi: 10.1038/nature22819. Epub 2017 Jun 14. Nature. 2017. PMID: 28614293 Free PMC article.
Housing temperature influences exercise training adaptations in mice.
Raun SH, Henriquez-Olguín C, Karavaeva I, Ali M, Møller LLV, Kot W, Castro-Mejía JL, Nielsen DS, Gerhart-Hines Z, Richter EA, Sylow L. Raun SH, et al. Nat Commun. 2020 Mar 25;11(1):1560. doi: 10.1038/s41467-020-15311-y. Nat Commun. 2020. PMID: 32214091 Free PMC article.
Lipolysis regulates major transcriptional programs in brown adipocytes.
Markussen LK, Rondini EA, Johansen OS, Madsen JGS, Sustarsic EG, Marcher AB, Hansen JB, Gerhart-Hines Z, Granneman JG, Mandrup S. Markussen LK, et al. Nat Commun. 2022 Jul 8;13(1):3956. doi: 10.1038/s41467-022-31525-8. Nat Commun. 2022. PMID: 35803907 Free PMC article.
Is lactate a driver of skin burn-induced adipose browning?
Lund J, Johansen VBI, Clemmensen C, Gerhart-Hines Z. Lund J, et al. Among authors: gerhart hines z. Am J Physiol Endocrinol Metab. 2023 Oct 1;325(4):E421-E422. doi: 10.1152/ajpendo.00251.2023. Am J Physiol Endocrinol Metab. 2023. PMID: 37812086 No abstract available.
Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis.
Sveidahl Johansen O, Ma T, Hansen JB, Markussen LK, Schreiber R, Reverte-Salisa L, Dong H, Christensen DP, Sun W, Gnad T, Karavaeva I, Nielsen TS, Kooijman S, Cero C, Dmytriyeva O, Shen Y, Razzoli M, O'Brien SL, Kuipers EN, Nielsen CH, Orchard W, Willemsen N, Jespersen NZ, Lundh M, Sustarsic EG, Hallgren CM, Frost M, McGonigle S, Isidor MS, Broholm C, Pedersen O, Hansen JB, Grarup N, Hansen T, Kjær A, Granneman JG, Babu MM, Calebiro D, Nielsen S, Rydén M, Soccio R, Rensen PCN, Treebak JT, Schwartz TW, Emanuelli B, Bartolomucci A, Pfeifer A, Zechner R, Scheele C, Mandrup S, Gerhart-Hines Z. Sveidahl Johansen O, et al. Cell. 2021 Jun 24;184(13):3502-3518.e33. doi: 10.1016/j.cell.2021.04.037. Epub 2021 May 27. Cell. 2021. PMID: 34048700 Free PMC article.
The anorectic and thermogenic effects of pharmacological lactate in male mice are confounded by treatment osmolarity and co-administered counterions.
Lund J, Breum AW, Gil C, Falk S, Sass F, Isidor MS, Dmytriyeva O, Ranea-Robles P, Mathiesen CV, Basse AL, Johansen OS, Fadahunsi N, Lund C, Nicolaisen TS, Klein AB, Ma T, Emanuelli B, Kleinert M, Sørensen CM, Gerhart-Hines Z, Clemmensen C. Lund J, et al. Among authors: gerhart hines z. Nat Metab. 2023 Apr;5(4):677-698. doi: 10.1038/s42255-023-00780-4. Epub 2023 Apr 13. Nat Metab. 2023. PMID: 37055619
MCT1 helps brown fat suck up succinate.
Lund J, Isidor MS, Gerhart-Hines Z. Lund J, et al. Among authors: gerhart hines z. Nat Metab. 2024 Mar;6(3):387-388. doi: 10.1038/s42255-024-00979-z. Nat Metab. 2024. PMID: 38378995 No abstract available.
ADRA1A-Gαq signalling potentiates adipocyte thermogenesis through CKB and TNAP.
Rahbani JF, Scholtes C, Lagarde DM, Hussain MF, Roesler A, Dykstra CB, Bunk J, Samborska B, O'Brien SL, Tripp E, Pacis A, Angueira AR, Johansen OS, Cinkornpumin J, Hossain I, Lynes MD, Zhang Y, White AP, Pastor WA, Chondronikola M, Sidossis L, Klein S, Kralli A, Cypess AM, Pedersen SB, Jessen N, Tseng YH, Gerhart-Hines Z, Seale P, Calebiro D, Giguère V, Kazak L. Rahbani JF, et al. Nat Metab. 2022 Nov;4(11):1459-1473. doi: 10.1038/s42255-022-00667-w. Epub 2022 Nov 7. Nat Metab. 2022. PMID: 36344764 Free PMC article.
58 results