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EGFR activation limits the response of liver cancer to lenvatinib.
Jin H, Shi Y, Lv Y, Yuan S, Ramirez CFA, Lieftink C, Wang L, Wang S, Wang C, Dias MH, Jochems F, Yang Y, Bosma A, Hijmans EM, de Groot MHP, Vegna S, Cui D, Zhou Y, Ling J, Wang H, Guo Y, Zheng X, Isima N, Wu H, Sun C, Beijersbergen RL, Akkari L, Zhou W, Zhai B, Qin W, Bernards R. Jin H, et al. Nature. 2021 Jul;595(7869):730-734. doi: 10.1038/s41586-021-03741-7. Epub 2021 Jul 21. Nature. 2021. PMID: 34290403
Rational combination of SHP2 and mTOR inhibition for the treatment of hepatocellular carcinoma.
Mulero-Sánchez A, Ramirez CFA, du Chatinier A, Wang H, Koomen SJI, Song JY, de Groot MHP, Lieftink C, Bosma A, Burylo A, van Tellingen O, Beijersbergen RL, Wang C, Akkari L, Bernards R, Mainardi S. Mulero-Sánchez A, et al. Mol Oncol. 2023 Jun;17(6):964-980. doi: 10.1002/1878-0261.13377. Epub 2023 Feb 9. Mol Oncol. 2023. PMID: 36650715 Free PMC article.
CD103+ regulatory T cells underlie resistance to radio-immunotherapy and impair CD8+ T cell activation in glioblastoma.
van Hooren L, Handgraaf SM, Kloosterman DJ, Karimi E, van Mil LWHG, Gassama AA, Solsona BG, de Groot MHP, Brandsma D, Quail DF, Walsh LA, Borst GR, Akkari L. van Hooren L, et al. Among authors: de groot mhp. Nat Cancer. 2023 May;4(5):665-681. doi: 10.1038/s43018-023-00547-6. Epub 2023 Apr 20. Nat Cancer. 2023. PMID: 37081259 Free PMC article.
Cancer cell genetics shaping of the tumor microenvironment reveals myeloid cell-centric exploitable vulnerabilities in hepatocellular carcinoma.
Ramirez CFA, Taranto D, Ando-Kuri M, de Groot MHP, Tsouri E, Huang Z, de Groot D, Kluin RJC, Kloosterman DJ, Verheij J, Xu J, Vegna S, Akkari L. Ramirez CFA, et al. Among authors: de groot mhp. Nat Commun. 2024 Mar 22;15(1):2581. doi: 10.1038/s41467-024-46835-2. Nat Commun. 2024. PMID: 38519484 Free PMC article.
Preliminary evidence of localizing CD8+ T-cell responses in COVID-19 patients with PET imaging.
Koenen HJPM, Kouijzer IJE, de Groot M, Peters S, Lobeek D, van Genugten EAJ, Diavatopoulos DA, van Oosten N, Gianotten S, Prokop MM, Netea MG, van de Veerdonk FL, Aarntzen EHJG. Koenen HJPM, et al. Among authors: de groot m. Front Med (Lausanne). 2024 May 15;11:1414415. doi: 10.3389/fmed.2024.1414415. eCollection 2024. Front Med (Lausanne). 2024. PMID: 38813383 Free PMC article.
Multiparametric MRI and 18F-PSMA-1007 PET/CT for the Detection of Clinically Significant Prostate Cancer.
Privé BM, Israël B, Janssen MJR, van der Leest MMG, de Rooij M, van Ipenburg JA, Jonker M, Peters SMB, de Groot M, Zámecnik P, Hoepping A, Bomers JG, Gotthardt M, Sedelaar JPM, Barentsz JO, van Oort IM, Nagarajah J. Privé BM, et al. Among authors: de groot m. Radiology. 2024 May;311(2):e231879. doi: 10.1148/radiol.231879. Radiology. 2024. PMID: 38771185
Improved Outcome of Allogeneic Transplantation in Older Patients Treated for Myeloid Malignancies Using Post-Transplantation Cyclophosphamide and Reduced Duration of Immune Suppression.
Morsink LM, Hazenberg CLE, Choi G, de Groot MR, Biswana A, Bellido M, Kooistra HAM, Bungener LB, Meijer K, Mulder AB, Huls G. Morsink LM, et al. Among authors: de groot mr. Transplant Cell Ther. 2024 May 11:S2666-6367(24)00406-8. doi: 10.1016/j.jtct.2024.05.009. Online ahead of print. Transplant Cell Ther. 2024. PMID: 38740138 Free article.
658 results