Barreiro EJ - Search Results

1

Novel VEGFR-2 inhibitors with an N-acylhydrazone scaffold.

Pauli FP, Martins JR, Paschoalin T, Ionta M, Barbosa MLC, Barreiro EJ. Pauli FP, et al. Among authors: barreiro ej. Arch Pharm (Weinheim). 2020 Nov;353(11):e2000130. doi: 10.1002/ardp.202000130. Epub 2020 Jul 15. Arch Pharm (Weinheim). 2020. PMID: 32667721

2

Antiplatelet properties of novel N-substituted-phenyl-1,2,3-triazole-4-acylhydrazone derivatives.

Cunha AC, Figueiredo JM, Tributino JL, Miranda AL, Castro HC, Zingali RB, Fraga CA, de Souza MC, Ferreira VF, Barreiro EJ. Cunha AC, et al. Among authors: barreiro ej. Bioorg Med Chem. 2003 May 1;11(9):2051-9. doi: 10.1016/s0968-0896(03)00055-5. Bioorg Med Chem. 2003. PMID: 12670656

3

Synthesis and anti-platelet activity of novel arylsulfonate--acylhydrazone derivatives, designed as antithrombotic candidates.

Lima LM, Frattani FS, Dos Santos JL, Castro HC, Fraga CA, Zingali RB, Barreiro EJ. Lima LM, et al. Among authors: barreiro ej. Eur J Med Chem. 2008 Feb;43(2):348-56. doi: 10.1016/j.ejmech.2007.03.032. Epub 2007 Apr 14. Eur J Med Chem. 2008. PMID: 17532545

4

Docking, synthesis and pharmacological activity of novel urea-derivatives designed as p38 MAPK inhibitors.

de Oliveira Lopes R, Romeiro NC, de Lima CK, Louback da Silva L, de Miranda AL, Nascimento PG, Cunha FQ, Barreiro EJ, Lima LM. de Oliveira Lopes R, et al. Among authors: barreiro ej. Eur J Med Chem. 2012 Aug;54:264-71. doi: 10.1016/j.ejmech.2012.05.006. Epub 2012 May 14. Eur J Med Chem. 2012. PMID: 22647219

5

Novel 2-chloro-4-anilino-quinazoline derivatives as EGFR and VEGFR-2 dual inhibitors.

Barbosa ML, Lima LM, Tesch R, Sant'Anna CM, Totzke F, Kubbutat MH, Schächtele C, Laufer SA, Barreiro EJ. Barbosa ML, et al. Among authors: barreiro ej. Eur J Med Chem. 2014 Jan;71:1-14. doi: 10.1016/j.ejmech.2013.10.058. Epub 2013 Oct 31. Eur J Med Chem. 2014. PMID: 24269511

6

Discovery of naphthyl-N-acylhydrazone p38α MAPK inhibitors with in vivo anti-inflammatory and anti-TNF-α activity.

Freitas RHCN, Cordeiro NM, Carvalho PR, Alves MA, Guedes IA, Valerio TS, Dardenne LE, Lima LM, Barreiro EJ, Fernandes PD, Fraga CAM. Freitas RHCN, et al. Among authors: barreiro ej. Chem Biol Drug Des. 2018 Feb;91(2):391-397. doi: 10.1111/cbdd.13085. Epub 2017 Sep 10. Chem Biol Drug Des. 2018. PMID: 28815968

7

Synthesis, X-ray diffraction study and pharmacological evaluation of 3-amino-4-methylthiophene-2-acylcarbohydrazones.

Herrmann S, Schübel T, Costa FN, Barbosa MLC, Ferreira FF, Dias TLMF, Araújo MV, Alexandre-Moreira MS, Lima LM, Laufer S, Barreiro EJ. Herrmann S, et al. Among authors: barreiro ej. An Acad Bras Cienc. 2018;90(1 Suppl 2):1073-1088. doi: 10.1590/0001-3765201820170796. An Acad Bras Cienc. 2018. PMID: 29873669 Free article.

8

A novel scaffold for EGFR inhibition: Introducing N-(3-(3-phenylureido)quinoxalin-6-yl) acrylamide derivatives.

do Amaral DN, Lategahn J, Fokoue HH, da Silva EMB, Sant'Anna CMR, Rauh D, Barreiro EJ, Laufer S, Lima LM. do Amaral DN, et al. Among authors: barreiro ej. Sci Rep. 2019 Jan 9;9(1):14. doi: 10.1038/s41598-018-36846-7. Sci Rep. 2019. PMID: 30626888 Free PMC article.

9

Bioisosteric Replacement of Arylamide-Linked Spine Residues with N-Acylhydrazones and Selenophenes as a Design Strategy to Novel Dibenzosuberone Derivatives as Type I 1/2 p38α MAP Kinase Inhibitors.

Pedreira JGB, Nahidino P, Kudolo M, Pantsar T, Berger BT, Forster M, Knapp S, Laufer S, Barreiro EJ. Pedreira JGB, et al. Among authors: barreiro ej. J Med Chem. 2020 Jul 9;63(13):7347-7354. doi: 10.1021/acs.jmedchem.0c00508. Epub 2020 Jun 11. J Med Chem. 2020. PMID: 32462866

10

Effect of S-Se Bioisosteric Exchange on Affinity and Intrinsic Efficacy of Novel N-acylhydrazone Derivatives at the Adenosine A_2A Receptor.

Pedreira JGB, Silva RR, Noël FG, Barreiro EJ. Pedreira JGB, et al. Among authors: barreiro ej. Molecules. 2021 Dec 4;26(23):7364. doi: 10.3390/molecules26237364. Molecules. 2021. PMID: 34885946 Free PMC article.

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