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ZNF410 Uniquely Activates the NuRD Component CHD4 to Silence Fetal Hemoglobin Expression.
Lan X, Ren R, Feng R, Ly LC, Lan Y, Zhang Z, Aboreden N, Qin K, Horton JR, Grevet JD, Mayuranathan T, Abdulmalik O, Keller CA, Giardine B, Hardison RC, Crossley M, Weiss MJ, Cheng X, Shi J, Blobel GA. Lan X, et al. Among authors: lan y. Mol Cell. 2021 Jan 21;81(2):239-254.e8. doi: 10.1016/j.molcel.2020.11.006. Epub 2020 Dec 9. Mol Cell. 2021. PMID: 33301730 Free PMC article.
Controllable genome editing with split-engineered base editors.
Berríos KN, Evitt NH, DeWeerd RA, Ren D, Luo M, Barka A, Wang T, Bartman CR, Lan Y, Green AM, Shi J, Kohli RM. Berríos KN, et al. Among authors: lan y. Nat Chem Biol. 2021 Dec;17(12):1262-1270. doi: 10.1038/s41589-021-00880-w. Epub 2021 Oct 18. Nat Chem Biol. 2021. PMID: 34663942 Free PMC article.
High-throughput Oligopaint screen identifies druggable 3D genome regulators.
Park DS, Nguyen SC, Isenhart R, Shah PP, Kim W, Barnett RJ, Chandra A, Luppino JM, Harke J, Wai M, Walsh PJ, Abdill RJ, Yang R, Lan Y, Yoon S, Yunker R, Kanemaki MT, Vahedi G, Phillips-Cremins JE, Jain R, Joyce EF. Park DS, et al. Among authors: lan y. Nature. 2023 Aug;620(7972):209-217. doi: 10.1038/s41586-023-06340-w. Epub 2023 Jul 12. Nature. 2023. PMID: 37438531
Cytoplasmic chromatin triggers inflammation in senescence and cancer.
Dou Z, Ghosh K, Vizioli MG, Zhu J, Sen P, Wangensteen KJ, Simithy J, Lan Y, Lin Y, Zhou Z, Capell BC, Xu C, Xu M, Kieckhaefer JE, Jiang T, Shoshkes-Carmel M, Tanim KMAA, Barber GN, Seykora JT, Millar SE, Kaestner KH, Garcia BA, Adams PD, Berger SL. Dou Z, et al. Among authors: lan y. Nature. 2017 Oct 19;550(7676):402-406. doi: 10.1038/nature24050. Epub 2017 Oct 4. Nature. 2017. PMID: 28976970 Free PMC article.
Dysregulation of the epigenetic landscape of normal aging in Alzheimer's disease.
Nativio R, Donahue G, Berson A, Lan Y, Amlie-Wolf A, Tuzer F, Toledo JB, Gosai SJ, Gregory BD, Torres C, Trojanowski JQ, Wang LS, Johnson FB, Bonini NM, Berger SL. Nativio R, et al. Among authors: lan y. Nat Neurosci. 2018 Apr;21(4):497-505. doi: 10.1038/s41593-018-0101-9. Epub 2018 Mar 5. Nat Neurosci. 2018. PMID: 29507413 Free PMC article.
Chromatin structure dynamics during the mitosis-to-G1 phase transition.
Zhang H, Emerson DJ, Gilgenast TG, Titus KR, Lan Y, Huang P, Zhang D, Wang H, Keller CA, Giardine B, Hardison RC, Phillips-Cremins JE, Blobel GA. Zhang H, et al. Among authors: lan y. Nature. 2019 Dec;576(7785):158-162. doi: 10.1038/s41586-019-1778-y. Epub 2019 Nov 27. Nature. 2019. PMID: 31776509 Free PMC article.
4,390 results