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Page 1
Metabolic implication of tigecycline as an efficacious second-line treatment for sorafenib-resistant hepatocellular carcinoma.
Meßner M, Schmitt S, Ardelt MA, Fröhlich T, Müller M, Pein H, Huber-Cantonati P, Ortler C, Koenig LM, Zobel L, Koeberle A, Arnold GJ, Rothenfußer S, Kiemer AK, Gerbes AL, Zischka H, Vollmar AM, Pachmayr J. Meßner M, et al. Among authors: pachmayr j. FASEB J. 2020 Sep;34(9):11860-11882. doi: 10.1096/fj.202001128R. Epub 2020 Jul 11. FASEB J. 2020. PMID: 32652772
Inhibition of Cyclin-Dependent Kinase 5: A Strategy to Improve Sorafenib Response in Hepatocellular Carcinoma Therapy.
Ardelt MA, Fröhlich T, Martini E, Müller M, Kanitz V, Atzberger C, Cantonati P, Meßner M, Posselt L, Lehr T, Wojtyniak JG, Ulrich M, Arnold GJ, König L, Parazzoli D, Zahler S, Rothenfußer S, Mayr D, Gerbes A, Scita G, Vollmar AM, Pachmayr J. Ardelt MA, et al. Among authors: pachmayr j. Hepatology. 2019 Jan;69(1):376-393. doi: 10.1002/hep.30190. Epub 2018 Dec 22. Hepatology. 2019. PMID: 30033593 Free PMC article.
PI(18:1/18:1) is a SCD1-derived lipokine that limits stress signaling.
Thürmer M, Gollowitzer A, Pein H, Neukirch K, Gelmez E, Waltl L, Wielsch N, Winkler R, Löser K, Grander J, Hotze M, Harder S, Döding A, Meßner M, Troisi F, Ardelt M, Schlüter H, Pachmayr J, Gutiérrez-Gutiérrez Ó, Rudolph KL, Thedieck K, Schulze-Späte U, González-Estévez C, Kosan C, Svatoš A, Kwiatkowski M, Koeberle A. Thürmer M, et al. Among authors: pachmayr j. Nat Commun. 2022 May 27;13(1):2982. doi: 10.1038/s41467-022-30374-9. Nat Commun. 2022. PMID: 35624087 Free PMC article.
Design and synthesis of tailored human caseinolytic protease P inhibitors.
Gronauer TF , Mandl MM , Lakemeyer M , Hackl MW , Meßner M , Korotkov VS , Pachmayr J , Sieber SA . Gronauer TF , et al. Among authors: pachmayr j. Chem Commun (Camb). 2018 Aug 28;54(70):9833-9836. doi: 10.1039/c8cc05265d. Chem Commun (Camb). 2018. PMID: 30109319
Analogues of Natural Chalcones as Efficient Inhibitors of AKR1C3.
Möller G, Temml V, Cala Peralta A, Gruet O, Richomme P, Séraphin D, Viault G, Kraus L, Huber-Cantonati P, Schopfhauser E, Pachmayr J, Tokarz J, Schuster D, Helesbeux JJ, Dyar KA. Möller G, et al. Among authors: pachmayr j. Metabolites. 2022 Jan 21;12(2):99. doi: 10.3390/metabo12020099. Metabolites. 2022. PMID: 35208174 Free PMC article.
Understanding the mechanism of action of pyrrolo[3,2-b]quinoxaline-derivatives as kinase inhibitors.
Unzue A, Jessen-Trefzer C, Spiliotopoulos D, Gaudio E, Tarantelli C, Dong J, Zhao H, Pachmayr J, Zahler S, Bernasconi E, Sartori G, Cascione L, Bertoni F, Śledź P, Caflisch A, Nevado C. Unzue A, et al. Among authors: pachmayr j. RSC Med Chem. 2020 May 19;11(6):665-675. doi: 10.1039/d0md00049c. eCollection 2020 Jun 1. RSC Med Chem. 2020. PMID: 33479666 Free PMC article.
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