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Cerebral cavernous malformations are driven by ADAMTS5 proteolysis of versican.
Hong CC, Tang AT, Detter MR, Choi JP, Wang R, Yang X, Guerrero AA, Wittig CF, Hobson N, Girard R, Lightle R, Moore T, Shenkar R, Polster SP, Goddard LM, Ren AA, Leu NA, Sterling S, Yang J, Li L, Chen M, Mericko-Ishizuka P, Dow LE, Watanabe H, Schwaninger M, Min W, Marchuk DA, Zheng X, Awad IA, Kahn ML. Hong CC, et al. Among authors: kahn ml. J Exp Med. 2020 Oct 5;217(10):e20200140. doi: 10.1084/jem.20200140. J Exp Med. 2020. PMID: 32648916 Free PMC article.
Lymphatic function is required prenatally for lung inflation at birth.
Jakus Z, Gleghorn JP, Enis DR, Sen A, Chia S, Liu X, Rawnsley DR, Yang Y, Hess PR, Zou Z, Yang J, Guttentag SH, Nelson CM, Kahn ML. Jakus Z, et al. Among authors: kahn ml. J Exp Med. 2014 May 5;211(5):815-26. doi: 10.1084/jem.20132308. Epub 2014 Apr 14. J Exp Med. 2014. PMID: 24733830 Free PMC article.
Cell Adhesion Mediated by VCAM-ITGα9 Interactions Enables Lymphatic Development.
Yang Y, Enis D, Zheng H, Chia S, Yang J, Chen M, Dhillon V, Papayannapoulou T, Kahn ML. Yang Y, et al. Among authors: kahn ml. Arterioscler Thromb Vasc Biol. 2015 May;35(5):1179-89. doi: 10.1161/ATVBAHA.114.304997. Epub 2015 Mar 5. Arterioscler Thromb Vasc Biol. 2015. PMID: 25745057 Free PMC article.
Cerebral cavernous malformations arise from endothelial gain of MEKK3-KLF2/4 signalling.
Zhou Z, Tang AT, Wong WY, Bamezai S, Goddard LM, Shenkar R, Zhou S, Yang J, Wright AC, Foley M, Arthur JS, Whitehead KJ, Awad IA, Li DY, Zheng X, Kahn ML. Zhou Z, et al. Among authors: kahn ml. Nature. 2016 Apr 7;532(7597):122-6. doi: 10.1038/nature17178. Epub 2016 Mar 30. Nature. 2016. PMID: 27027284 Free PMC article.
250 results