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STK11 (LKB1) missense somatic mutant isoforms promote tumor growth, motility and inflammation.
Granado-Martínez P, Garcia-Ortega S, González-Sánchez E, McGrail K, Selgas R, Grueso J, Gil R, Naldaiz-Gastesi N, Rhodes AC, Hernandez-Losa J, Ferrer B, Canals F, Villanueva J, Méndez O, Espinosa-Gil S, Lizcano JM, Muñoz-Couselo E, García-Patos V, Recio JA. Granado-Martínez P, et al. Among authors: selgas r. Commun Biol. 2020 Jul 9;3(1):366. doi: 10.1038/s42003-020-1092-0. Commun Biol. 2020. PMID: 32647375 Free PMC article.
CTGF promotes inflammatory cell infiltration of the renal interstitium by activating NF-kappaB.
Sánchez-López E, Rayego S, Rodrigues-Díez R, Rodriguez JS, Rodrigues-Díez R, Rodríguez-Vita J, Carvajal G, Aroeira LS, Selgas R, Mezzano SA, Ortiz A, Egido J, Ruiz-Ortega M. Sánchez-López E, et al. Among authors: selgas r. J Am Soc Nephrol. 2009 Jul;20(7):1513-26. doi: 10.1681/ASN.2008090999. Epub 2009 May 7. J Am Soc Nephrol. 2009. PMID: 19423687 Free PMC article.
Fn14 in podocytes and proteinuric kidney disease.
Sanchez-Niño MD, Poveda J, Sanz AB, Mezzano S, Carrasco S, Fernandez-Fernandez B, Burkly LC, Nair V, Kretzler M, Hodgin JB, Ruiz-Ortega M, Selgas R, Egido J, Ortiz A. Sanchez-Niño MD, et al. Among authors: selgas r. Biochim Biophys Acta. 2013 Dec;1832(12):2232-43. doi: 10.1016/j.bbadis.2013.08.010. Epub 2013 Aug 30. Biochim Biophys Acta. 2013. PMID: 23999007 Free article.
[Connective tissue growth factor (CTGF): a key factor in the onset and progression of kidney damage].
Sánchez-López E, Rodrigues Díez R, Rodríguez Vita J, Rayego Mateos S, Rodrigues Díez RR, Rodríguez García E, Lavoz Barria C, Mezzano S, Egido J, Ortiz A, Ruiz-Ortega M, Selgas R. Sánchez-López E, et al. Among authors: selgas r. Nefrologia. 2009;29(5):382-91. doi: 10.3265/Nefrologia.2009.29.5.5429.en.full. Nefrologia. 2009. PMID: 19820749 Free article. Review. Spanish.
The inflammatory cytokines TWEAK and TNFα reduce renal klotho expression through NFκB.
Moreno JA, Izquierdo MC, Sanchez-Niño MD, Suárez-Alvarez B, Lopez-Larrea C, Jakubowski A, Blanco J, Ramirez R, Selgas R, Ruiz-Ortega M, Egido J, Ortiz A, Sanz AB. Moreno JA, et al. Among authors: selgas r. J Am Soc Nephrol. 2011 Jul;22(7):1315-25. doi: 10.1681/ASN.2010101073. Epub 2011 Jun 30. J Am Soc Nephrol. 2011. PMID: 21719790 Free PMC article.
A nanoconjugate Apaf-1 inhibitor protects mesothelial cells from cytokine-induced injury.
Santamaría B, Benito-Martin A, Ucero AC, Aroeira LS, Reyero A, Vicent MJ, Orzáez M, Celdrán A, Esteban J, Selgas R, Ruíz-Ortega M, Cabrera ML, Egido J, Pérez-Payá E, Ortiz A. Santamaría B, et al. Among authors: selgas r. PLoS One. 2009 Aug 13;4(8):e6634. doi: 10.1371/journal.pone.0006634. PLoS One. 2009. PMID: 19675677 Free PMC article.
Macrophages and recently identified forms of cell death.
Sanz AB, Sanchez-Niño MD, Izquierdo MC, Gonzalez-Espinoza L, Ucero AC, Poveda J, Ruiz-Andres O, Ruiz-Ortega M, Selgas R, Egido J, Ortiz A. Sanz AB, et al. Among authors: selgas r. Int Rev Immunol. 2014 Jan;33(1):9-22. doi: 10.3109/08830185.2013.771183. Epub 2013 Jun 26. Int Rev Immunol. 2014. PMID: 23802146 Review.
IL-17A is a novel player in dialysis-induced peritoneal damage.
Rodrigues-Díez R, Aroeira LS, Orejudo M, Bajo MA, Heffernan JJ, Rodrigues-Díez RR, Rayego-Mateos S, Ortiz A, Gonzalez-Mateo G, López-Cabrera M, Selgas R, Egido J, Ruiz-Ortega M. Rodrigues-Díez R, et al. Among authors: selgas r. Kidney Int. 2014 Aug;86(2):303-15. doi: 10.1038/ki.2014.33. Epub 2014 Feb 19. Kidney Int. 2014. PMID: 24552849 Free article.
389 results