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To translocate or not: that is the problem.
Lencer WI, Tweten RK. Lencer WI, et al. Cell Host Microbe. 2011 Sep 15;10(3):179-80. doi: 10.1016/j.chom.2011.08.009. Cell Host Microbe. 2011. PMID: 21925105 Free PMC article.
The unfolded protein response element IRE1α senses bacterial proteins invading the ER to activate RIG-I and innate immune signaling.
Cho JA, Lee AH, Platzer B, Cross BCS, Gardner BM, De Luca H, Luong P, Harding HP, Glimcher LH, Walter P, Fiebiger E, Ron D, Kagan JC, Lencer WI. Cho JA, et al. Among authors: lencer wi. Cell Host Microbe. 2013 May 15;13(5):558-569. doi: 10.1016/j.chom.2013.03.011. Cell Host Microbe. 2013. PMID: 23684307 Free PMC article. Retracted.
Depletion of the apical endosome in response to viruses and bacterial toxins provides cell-autonomous host defense at mucosal surfaces.
Maeda K, Zachos NC, Orzalli MH, Schmieder SS, Chang D, Bugda Gwilt K, Doucet M, Baetz NW, Lee S, Crawford SE, Estes MK, Kagan JC, Turner JR, Lencer WI. Maeda K, et al. Among authors: lencer wi. Cell Host Microbe. 2022 Feb 9;30(2):216-231.e5. doi: 10.1016/j.chom.2021.12.011. Cell Host Microbe. 2022. PMID: 35143768 Free PMC article.
Lipid sorting by ceramide structure from plasma membrane to ER for the cholera toxin receptor ganglioside GM1.
Chinnapen DJ, Hsieh WT, te Welscher YM, Saslowsky DE, Kaoutzani L, Brandsma E, D'Auria L, Park H, Wagner JS, Drake KR, Kang M, Benjamin T, Ullman MD, Costello CE, Kenworthy AK, Baumgart T, Massol RH, Lencer WI. Chinnapen DJ, et al. Among authors: lencer wi. Dev Cell. 2012 Sep 11;23(3):573-86. doi: 10.1016/j.devcel.2012.08.002. Dev Cell. 2012. PMID: 22975326 Free PMC article.
Membrane traffic and the cellular uptake of cholera toxin.
Lencer WI, Hirst TR, Holmes RK. Lencer WI, et al. Biochim Biophys Acta. 1999 Jul 8;1450(3):177-90. doi: 10.1016/s0167-4889(99)00070-1. Biochim Biophys Acta. 1999. PMID: 10395933 Free article. Review.
172 results