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Graft IL-33 regulates infiltrating macrophages to protect against chronic rejection.
Li T, Zhang Z, Bartolacci JG, Dwyer GK, Liu Q, Mathews LR, Velayutham M, Roessing AS, Lee YC, Dai H, Shiva S, Oberbarnscheidt MH, Dziki JL, Mullet SJ, Wendell SG, Wilkinson JD, Webber SA, Wood-Trageser M, Watkins SC, Demetris AJ, Hussey GS, Badylak SF, Turnquist HR. Li T, et al. Among authors: turnquist hr. J Clin Invest. 2020 Oct 1;130(10):5397-5412. doi: 10.1172/JCI133008. J Clin Invest. 2020. PMID: 32644975 Free PMC article.
IL-33 expands suppressive CD11b+ Gr-1(int) and regulatory T cells, including ST2L+ Foxp3+ cells, and mediates regulatory T cell-dependent promotion of cardiac allograft survival.
Turnquist HR, Zhao Z, Rosborough BR, Liu Q, Castellaneta A, Isse K, Wang Z, Lang M, Stolz DB, Zheng XX, Demetris AJ, Liew FY, Wood KJ, Thomson AW. Turnquist HR, et al. J Immunol. 2011 Nov 1;187(9):4598-610. doi: 10.4049/jimmunol.1100519. Epub 2011 Sep 26. J Immunol. 2011. PMID: 21949025 Free PMC article.
IL-12hi rapamycin-conditioned dendritic cells mediate IFN-γ-dependent apoptosis of alloreactive CD4+ T cells in vitro and reduce lethal graft-versus-host disease.
Stenger EO, Rosborough BR, Mathews LR, Ma H, Mapara MY, Thomson AW, Turnquist HR. Stenger EO, et al. Among authors: turnquist hr. Biol Blood Marrow Transplant. 2014 Feb;20(2):192-201. doi: 10.1016/j.bbmt.2013.11.007. Epub 2013 Nov 12. Biol Blood Marrow Transplant. 2014. PMID: 24239650 Free PMC article.
The IL-33/ST2 axis augments effector T-cell responses during acute GVHD.
Reichenbach DK, Schwarze V, Matta BM, Tkachev V, Lieberknecht E, Liu Q, Koehn BH, Pfeifer D, Taylor PA, Prinz G, Dierbach H, Stickel N, Beck Y, Warncke M, Junt T, Schmitt-Graeff A, Nakae S, Follo M, Wertheimer T, Schwab L, Devlin J, Watkins SC, Duyster J, Ferrara JL, Turnquist HR, Zeiser R, Blazar BR. Reichenbach DK, et al. Among authors: turnquist hr. Blood. 2015 May 14;125(20):3183-92. doi: 10.1182/blood-2014-10-606830. Epub 2015 Mar 26. Blood. 2015. PMID: 25814531 Free PMC article.
IL-33-mediated IL-13 secretion by ST2+ Tregs controls inflammation after lung injury.
Liu Q, Dwyer GK, Zhao Y, Li H, Mathews LR, Chakka AB, Chandran UR, Demetris JA, Alcorn JF, Robinson KM, Ortiz LA, Pitt BR, Thomson AW, Fan MH, Billiar TR, Turnquist HR. Liu Q, et al. Among authors: turnquist hr. JCI Insight. 2019 Mar 21;4(6):e123919. doi: 10.1172/jci.insight.123919. eCollection 2019 Mar 21. JCI Insight. 2019. PMID: 30779711 Free PMC article.
90 results