Lesperance J - Search Results

1

Characterization of G-CSF receptor expression in medulloblastoma.

Paul MR, Huo Y, Liu A, Lesperance J, Garancher A, Wechsler-Reya RJ, Zage PE. Paul MR, et al. Among authors: lesperance j. Neurooncol Adv. 2020 May 27;2(1):vdaa062. doi: 10.1093/noajnl/vdaa062. eCollection 2020 Jan-Dec. Neurooncol Adv. 2020. PMID: 32642714 Free PMC article.

2

The multikinase inhibitor RXDX-105 is effective against neuroblastoma in vitro and in vivo.

Flynn SM, Lesperance J, Macias A, Phanhthilath N, Paul MR, Kim JW, Tamayo P, Zage PE. Flynn SM, et al. Among authors: lesperance j. Oncotarget. 2019 Oct 29;10(59):6323-6333. doi: 10.18632/oncotarget.27259. eCollection 2019 Oct 29. Oncotarget. 2019. PMID: 31695841 Free PMC article.

3

Mechanisms of Efficacy of the FGFR1-3 Inhibitor AZD4547 in Pediatric Solid Tumor Models.

Phanhthilath N, Hakim S, Su C, Liu A, Subramonian D, Lesperance J, Zage PE. Phanhthilath N, et al. Among authors: lesperance j. Invest New Drugs. 2020 Dec;38(6):1677-1686. doi: 10.1007/s10637-020-00933-2. Epub 2020 May 20. Invest New Drugs. 2020. PMID: 32436058

4

The Potential Functional Roles of NME1 Histidine Kinase Activity in Neuroblastoma Pathogenesis.

Adam K, Lesperance J, Hunter T, Zage PE. Adam K, et al. Among authors: lesperance j. Int J Mol Sci. 2020 May 7;21(9):3319. doi: 10.3390/ijms21093319. Int J Mol Sci. 2020. PMID: 32392889 Free PMC article.

5

Regorafenib is effective against neuroblastoma in vitro and in vivo and inhibits the RAS/MAPK, PI3K/Akt/mTOR and Fos/Jun pathways.

Subramonian D, Phanhthilath N, Rinehardt H, Flynn S, Huo Y, Zhang J, Messer K, Mo Q, Huang S, Lesperance J, Zage PE. Subramonian D, et al. Among authors: lesperance j. Br J Cancer. 2020 Aug;123(4):568-579. doi: 10.1038/s41416-020-0905-8. Epub 2020 May 27. Br J Cancer. 2020. PMID: 32457362 Free PMC article.

6

Proapoptotic PUMA targets stem-like breast cancer cells to suppress metastasis.

Sun Q, Lesperance J, Wettersten H, Luterstein E, DeRose YS, Welm A, Cheresh DA, Desgrosellier JS. Sun Q, et al. Among authors: lesperance j. J Clin Invest. 2018 Jan 2;128(1):531-544. doi: 10.1172/JCI93707. Epub 2017 Dec 11. J Clin Invest. 2018. PMID: 29227280 Free PMC article.

7

Antitumor activity of rapamycin in a transgenic mouse model of ErbB2-dependent human breast cancer.

Liu M, Howes A, Lesperance J, Stallcup WB, Hauser CA, Kadoya K, Oshima RG, Abraham RT. Liu M, et al. Among authors: lesperance j. Cancer Res. 2005 Jun 15;65(12):5325-36. doi: 10.1158/0008-5472.CAN-04-4589. Cancer Res. 2005. PMID: 15958580

8

Maternal embryonic leucine zipper kinase is upregulated and required in mammary tumor-initiating cells in vivo.

Hebbard LW, Maurer J, Miller A, Lesperance J, Hassell J, Oshima RG, Terskikh AV. Hebbard LW, et al. Among authors: lesperance j. Cancer Res. 2010 Nov 1;70(21):8863-73. doi: 10.1158/0008-5472.CAN-10-1295. Epub 2010 Sep 22. Cancer Res. 2010. PMID: 20861186 Free PMC article.

9

An integrin β₃-KRAS-RalB complex drives tumour stemness and resistance to EGFR inhibition.

Seguin L, Kato S, Franovic A, Camargo MF, Lesperance J, Elliott KC, Yebra M, Mielgo A, Lowy AM, Husain H, Cascone T, Diao L, Wang J, Wistuba II, Heymach JV, Lippman SM, Desgrosellier JS, Anand S, Weis SM, Cheresh DA. Seguin L, et al. Among authors: lesperance j. Nat Cell Biol. 2014 May;16(5):457-68. doi: 10.1038/ncb2953. Epub 2014 Apr 20. Nat Cell Biol. 2014. PMID: 24747441 Free PMC article.

10

Role of Gab2 in mammary tumorigenesis and metastasis.

Ke Y, Wu D, Princen F, Nguyen T, Pang Y, Lesperance J, Muller WJ, Oshima RG, Feng GS. Ke Y, et al. Among authors: lesperance j. Oncogene. 2007 Jul 26;26(34):4951-60. doi: 10.1038/sj.onc.1210315. Epub 2007 Feb 19. Oncogene. 2007. PMID: 17310989

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