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Mitochondrial oxidative stress and respiratory chain dysfunction account for liver toxicity during amiodarone but not dronedarone administration.
Serviddio G, Bellanti F, Giudetti AM, Gnoni GV, Capitanio N, Tamborra R, Romano AD, Quinto M, Blonda M, Vendemiale G, Altomare E. Serviddio G, et al. Among authors: tamborra r. Free Radic Biol Med. 2011 Dec 15;51(12):2234-42. doi: 10.1016/j.freeradbiomed.2011.09.004. Epub 2011 Sep 17. Free Radic Biol Med. 2011. PMID: 21971348
Propofol but not sevoflurane prevents mitochondrial dysfunction and oxidative stress by limiting HIF-1α activation in hepatic ischemia/reperfusion injury.
Bellanti F, Mirabella L, Mitarotonda D, Blonda M, Tamborra R, Cinnella G, Fersini A, Ambrosi A, Dambrosio M, Vendemiale G, Serviddio G. Bellanti F, et al. Among authors: tamborra r. Free Radic Biol Med. 2016 Jul;96:323-33. doi: 10.1016/j.freeradbiomed.2016.05.002. Epub 2016 May 3. Free Radic Biol Med. 2016. PMID: 27154980
Synergistic interaction of fatty acids and oxysterols impairs mitochondrial function and limits liver adaptation during nafld progression.
Bellanti F, Villani R, Tamborra R, Blonda M, Iannelli G, di Bello G, Facciorusso A, Poli G, Iuliano L, Avolio C, Vendemiale G, Serviddio G. Bellanti F, et al. Among authors: tamborra r. Redox Biol. 2018 May;15:86-96. doi: 10.1016/j.redox.2017.11.016. Epub 2017 Dec 5. Redox Biol. 2018. PMID: 29220698 Free PMC article.
26 results