Ostrom RS - Search Results

1

Phosphodiesterase isoforms and cAMP compartments in the development of new therapies for obstructive pulmonary diseases.

Schmidt M, Cattani-Cavalieri I, Nuñez FJ, Ostrom RS. Schmidt M, et al. Among authors: ostrom rs. Curr Opin Pharmacol. 2020 Apr;51:34-42. doi: 10.1016/j.coph.2020.05.002. Epub 2020 Jul 1. Curr Opin Pharmacol. 2020. PMID: 32622335 Free PMC article. Review.

2

cAMP Signaling Compartmentation: Adenylyl Cyclases as Anchors of Dynamic Signaling Complexes.

Johnstone TB, Agarwal SR, Harvey RD, Ostrom RS. Johnstone TB, et al. Among authors: ostrom rs. Mol Pharmacol. 2018 Apr;93(4):270-276. doi: 10.1124/mol.117.110825. Epub 2017 Dec 7. Mol Pharmacol. 2018. PMID: 29217670 Free PMC article. Review.

3

Transforming Growth Factor-β1 Decreases β₂-Agonist-induced Relaxation in Human Airway Smooth Muscle.

Ojiaku CA, Chung E, Parikh V, Williams JK, Schwab A, Fuentes AL, Corpuz ML, Lui V, Paek S, Bexiga NM, Narayan S, Nunez FJ, Ahn K, Ostrom RS, An SS, Panettieri RA Jr. Ojiaku CA, et al. Among authors: ostrom rs. Am J Respir Cell Mol Biol. 2019 Aug;61(2):209-218. doi: 10.1165/rcmb.2018-0301OC. Am J Respir Cell Mol Biol. 2019. PMID: 30742476 Free PMC article.

4

Agonist-specific desensitization of PGE₂-stimulated cAMP signaling due to upregulated phosphodiesterase expression in human lung fibroblasts.

Nunez FJ, Schulte NA, Fogel DM, Michalski J, Rennard SI, Penn RB, Toews ML, Ostrom RS. Nunez FJ, et al. Among authors: ostrom rs. Naunyn Schmiedebergs Arch Pharmacol. 2020 May;393(5):843-856. doi: 10.1007/s00210-019-01800-5. Epub 2019 Dec 28. Naunyn Schmiedebergs Arch Pharmacol. 2020. PMID: 31884570 Free PMC article.

5

Glucocorticoids rapidly activate cAMP production via G_αs to initiate non-genomic signaling that contributes to one-third of their canonical genomic effects.

Nuñez FJ, Johnstone TB, Corpuz ML, Kazarian AG, Mohajer NN, Tliba O, Panettieri RA Jr, Koziol-White C, Roosan MR, Ostrom RS. Nuñez FJ, et al. Among authors: ostrom rs. FASEB J. 2020 Feb;34(2):2882-2895. doi: 10.1096/fj.201902521R. Epub 2019 Dec 27. FASEB J. 2020. PMID: 31908022 Free PMC article.

6

[No title available]

[No authors listed] [No authors listed] PMID: 35552981

7

[No title available]

[No authors listed] [No authors listed] PMID: 35555931

8

Localization of adenylyl cyclase isoforms and G protein-coupled receptors in vascular smooth muscle cells: expression in caveolin-rich and noncaveolin domains.

Ostrom RS, Liu X, Head BP, Gregorian C, Seasholtz TM, Insel PA. Ostrom RS, et al. Mol Pharmacol. 2002 Nov;62(5):983-92. doi: 10.1124/mol.62.5.983. Mol Pharmacol. 2002. PMID: 12391260 Free article.

9

Compartmentalized cAMP responses to prostaglandin EP₂ receptor activation in human airway smooth muscle cells.

Agarwal SR, Miyashiro K, Latt H, Ostrom RS, Harvey RD. Agarwal SR, et al. Among authors: ostrom rs. Br J Pharmacol. 2017 Aug;174(16):2784-2796. doi: 10.1111/bph.13904. Epub 2017 Jul 12. Br J Pharmacol. 2017. PMID: 28603838 Free PMC article.

10

Effect of Adenylyl Cyclase Type 6 on Localized Production of cAMP by β-2 Adrenoceptors in Human Airway Smooth-Muscle Cells.

Agarwal SR, Fiore C, Miyashiro K, Ostrom RS, Harvey RD. Agarwal SR, et al. Among authors: ostrom rs. J Pharmacol Exp Ther. 2019 Jul;370(1):104-110. doi: 10.1124/jpet.119.256594. Epub 2019 May 8. J Pharmacol Exp Ther. 2019. PMID: 31068382 Free PMC article.

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