Wade PA - Search Results

1

Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms.

Gao L, Emperle M, Guo Y, Grimm SA, Ren W, Adam S, Uryu H, Zhang ZM, Chen D, Yin J, Dukatz M, Anteneh H, Jurkowska RZ, Lu J, Wang Y, Bashtrykov P, Wade PA, Wang GG, Jeltsch A, Song J. Gao L, et al. Among authors: wade pa. Nat Commun. 2020 Jul 3;11(1):3355. doi: 10.1038/s41467-020-17109-4. Nat Commun. 2020. PMID: 32620778 Free PMC article.

2

DNA methylation profiling in human B cells reveals immune regulatory elements and epigenetic plasticity at Alu elements during B-cell activation.

Lai AY, Mav D, Shah R, Grimm SA, Phadke D, Hatzi K, Melnick A, Geigerman C, Sobol SE, Jaye DL, Wade PA. Lai AY, et al. Among authors: wade pa. Genome Res. 2013 Dec;23(12):2030-41. doi: 10.1101/gr.155473.113. Epub 2013 Sep 6. Genome Res. 2013. PMID: 24013550 Free PMC article.

3

MBD3 localizes at promoters, gene bodies and enhancers of active genes.

Shimbo T, Du Y, Grimm SA, Dhasarathy A, Mav D, Shah RR, Shi H, Wade PA. Shimbo T, et al. Among authors: wade pa. PLoS Genet. 2013;9(12):e1004028. doi: 10.1371/journal.pgen.1004028. Epub 2013 Dec 26. PLoS Genet. 2013. PMID: 24385926 Free PMC article.

4

Fine-tuning of epigenetic regulation with respect to promoter CpG content in a cell type-specific manner.

Li R, Mav D, Grimm SA, Jothi R, Shah R, Wade PA. Li R, et al. Among authors: wade pa. Epigenetics. 2014 May;9(5):747-59. doi: 10.4161/epi.28075. Epub 2014 Feb 12. Epigenetics. 2014. PMID: 24521667 Free PMC article.

5

Obesity, rather than diet, drives epigenomic alterations in colonic epithelium resembling cancer progression.

Li R, Grimm SA, Chrysovergis K, Kosak J, Wang X, Du Y, Burkholder A, Janardhan K, Mav D, Shah R, Eling TE, Wade PA. Li R, et al. Among authors: wade pa. Cell Metab. 2014 Apr 1;19(4):702-11. doi: 10.1016/j.cmet.2014.03.012. Cell Metab. 2014. PMID: 24703701 Free PMC article.

6

Breast tumor specific mutation in GATA3 affects physiological mechanisms regulating transcription factor turnover.

Adomas AB, Grimm SA, Malone C, Takaku M, Sims JK, Wade PA. Adomas AB, et al. Among authors: wade pa. BMC Cancer. 2014 Apr 22;14:278. doi: 10.1186/1471-2407-14-278. BMC Cancer. 2014. PMID: 24758297 Free PMC article.

7

GATA3 in Breast Cancer: Tumor Suppressor or Oncogene?

Takaku M, Grimm SA, Wade PA. Takaku M, et al. Among authors: wade pa. Gene Expr. 2015;16(4):163-8. doi: 10.3727/105221615X14399878166113. Gene Expr. 2015. PMID: 26637396 Free PMC article. Review.

8

GATA3-dependent cellular reprogramming requires activation-domain dependent recruitment of a chromatin remodeler.

Takaku M, Grimm SA, Shimbo T, Perera L, Menafra R, Stunnenberg HG, Archer TK, Machida S, Kurumizaka H, Wade PA. Takaku M, et al. Among authors: wade pa. Genome Biol. 2016 Feb 27;17:36. doi: 10.1186/s13059-016-0897-0. Genome Biol. 2016. PMID: 26922637 Free PMC article.

9

Epigenetic Perturbations by Arg882-Mutated DNMT3A Potentiate Aberrant Stem Cell Gene-Expression Program and Acute Leukemia Development.

Lu R, Wang P, Parton T, Zhou Y, Chrysovergis K, Rockowitz S, Chen WY, Abdel-Wahab O, Wade PA, Zheng D, Wang GG. Lu R, et al. Among authors: wade pa. Cancer Cell. 2016 Jul 11;30(1):92-107. doi: 10.1016/j.ccell.2016.05.008. Epub 2016 Jun 23. Cancer Cell. 2016. PMID: 27344947 Free PMC article.

10

Proteins That Read DNA Methylation.

Shimbo T, Wade PA. Shimbo T, et al. Among authors: wade pa. Adv Exp Med Biol. 2016;945:303-320. doi: 10.1007/978-3-319-43624-1_13. Adv Exp Med Biol. 2016. PMID: 27826844 Review.

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